Ability of MultiColor scanning laser ophthalmoscope to detect non-glaucomatous retinal nerve fiber layer defects in eyes with retinal diseases
Abstract Purpose To compare the ability of ocular fundus images obtained by Spectralis MultiColor scanning laser ophthalmoscope (MC-SLO) to that obtained by conventional color fundus images (CF) in detecting non-glaucomatous nerve fiber layer defects (NFLDs). Methods A cross-sectional, retrospective...
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| Format: | Article |
| Language: | English |
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BMC
2018-12-01
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| Series: | BMC Ophthalmology |
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| Online Access: | http://link.springer.com/article/10.1186/s12886-018-0995-8 |
| _version_ | 1818521637835767808 |
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| author | Hiroto Terasaki Shozo Sonoda Naoko Kakiuchi Hideki Shiihara Takehiro Yamashita Taiji Sakamoto |
| author_facet | Hiroto Terasaki Shozo Sonoda Naoko Kakiuchi Hideki Shiihara Takehiro Yamashita Taiji Sakamoto |
| author_sort | Hiroto Terasaki |
| collection | DOAJ |
| description | Abstract Purpose To compare the ability of ocular fundus images obtained by Spectralis MultiColor scanning laser ophthalmoscope (MC-SLO) to that obtained by conventional color fundus images (CF) in detecting non-glaucomatous nerve fiber layer defects (NFLDs). Methods A cross-sectional, retrospective study. Patients with retinal diseases who had ocular examination with both the MC-SLO and CF instruments at the Kagoshima University from December 2016 to February 2017 were studied. Eyes that had NFLDs with non-glaucomatous optic discs were analyzed. The visibility of the NFLDs was classified into three grades: grade 0, not visible; grade 1, barely visible; and grade 2, clearly visible. The NFLD grade for blue, green, and red scanning lights of the MC-SLO, merged images with three wavelengths and the color and red-free images were determined by two ophthalmologists. These scores were compared by Steel-Dwass tests. Results Thirty-one eyes of 26 patients with a mean age of 63.1 ± 11.2 years were studied. There were 14 eyes with diabetic retinopathy, 11 eyes with age-related macular degeneration, 3 eyes with a branch retinal vein occlusion, and 3 eyes with an epiretinal membrane/macular hole. Both the intra-rater (0.631–0.790) and inter-rater (0.637–0.733) agreements were good. NFLDs were detected by the blue wavelength in all cases and by green wavelength and merged wavelengths in 90.3% of the images. The mean NFLD grade was 1.58 ± 0.49 for blue light images, 1.13 ± 0.54 for green light images, 0.07 ± 0.24 for red light images, and 1.16 ± 0.56 for merged images. The NFLD score for blue wavelength was significantly higher than that for green and red wavelength images (P < 0.05 and P < 0.01) but not significantly higher than that for the merged images. NFLDs were detected in 12 eyes (38.7%) in the color images and 16 eyes (51.6%) in the red-free images. The NFLD score for the CF and the red-free image was 0.41 ± 0.55 and 0.70 ± 0.67 which is significantly lower than that of blue MC-SLO images. Conclusion The images obtained by MC-SLO are superior to that obtained by CF in detecting NFLDs in eyes with retinal diseases. We recommend MC-SLO imaging to screen for NFLDs in eyes with retinal diseases. |
| first_indexed | 2024-12-11T01:54:01Z |
| format | Article |
| id | doaj.art-c2bdac1e0df04956a1bf891096d239c2 |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-12-11T01:54:01Z |
| publishDate | 2018-12-01 |
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| spelling | doaj.art-c2bdac1e0df04956a1bf891096d239c22022-12-22T01:24:40ZengBMCBMC Ophthalmology1471-24152018-12-011811710.1186/s12886-018-0995-8Ability of MultiColor scanning laser ophthalmoscope to detect non-glaucomatous retinal nerve fiber layer defects in eyes with retinal diseasesHiroto Terasaki0Shozo Sonoda1Naoko Kakiuchi2Hideki Shiihara3Takehiro Yamashita4Taiji Sakamoto5Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental SciencesDepartment of Ophthalmology, Kagoshima University Graduate School of Medical and Dental SciencesAbstract Purpose To compare the ability of ocular fundus images obtained by Spectralis MultiColor scanning laser ophthalmoscope (MC-SLO) to that obtained by conventional color fundus images (CF) in detecting non-glaucomatous nerve fiber layer defects (NFLDs). Methods A cross-sectional, retrospective study. Patients with retinal diseases who had ocular examination with both the MC-SLO and CF instruments at the Kagoshima University from December 2016 to February 2017 were studied. Eyes that had NFLDs with non-glaucomatous optic discs were analyzed. The visibility of the NFLDs was classified into three grades: grade 0, not visible; grade 1, barely visible; and grade 2, clearly visible. The NFLD grade for blue, green, and red scanning lights of the MC-SLO, merged images with three wavelengths and the color and red-free images were determined by two ophthalmologists. These scores were compared by Steel-Dwass tests. Results Thirty-one eyes of 26 patients with a mean age of 63.1 ± 11.2 years were studied. There were 14 eyes with diabetic retinopathy, 11 eyes with age-related macular degeneration, 3 eyes with a branch retinal vein occlusion, and 3 eyes with an epiretinal membrane/macular hole. Both the intra-rater (0.631–0.790) and inter-rater (0.637–0.733) agreements were good. NFLDs were detected by the blue wavelength in all cases and by green wavelength and merged wavelengths in 90.3% of the images. The mean NFLD grade was 1.58 ± 0.49 for blue light images, 1.13 ± 0.54 for green light images, 0.07 ± 0.24 for red light images, and 1.16 ± 0.56 for merged images. The NFLD score for blue wavelength was significantly higher than that for green and red wavelength images (P < 0.05 and P < 0.01) but not significantly higher than that for the merged images. NFLDs were detected in 12 eyes (38.7%) in the color images and 16 eyes (51.6%) in the red-free images. The NFLD score for the CF and the red-free image was 0.41 ± 0.55 and 0.70 ± 0.67 which is significantly lower than that of blue MC-SLO images. Conclusion The images obtained by MC-SLO are superior to that obtained by CF in detecting NFLDs in eyes with retinal diseases. We recommend MC-SLO imaging to screen for NFLDs in eyes with retinal diseases.http://link.springer.com/article/10.1186/s12886-018-0995-8Non-glaucomatous NFLDScanning laser ophthalmoscopeSpectralisMultiColor |
| spellingShingle | Hiroto Terasaki Shozo Sonoda Naoko Kakiuchi Hideki Shiihara Takehiro Yamashita Taiji Sakamoto Ability of MultiColor scanning laser ophthalmoscope to detect non-glaucomatous retinal nerve fiber layer defects in eyes with retinal diseases BMC Ophthalmology Non-glaucomatous NFLD Scanning laser ophthalmoscope Spectralis MultiColor |
| title | Ability of MultiColor scanning laser ophthalmoscope to detect non-glaucomatous retinal nerve fiber layer defects in eyes with retinal diseases |
| title_full | Ability of MultiColor scanning laser ophthalmoscope to detect non-glaucomatous retinal nerve fiber layer defects in eyes with retinal diseases |
| title_fullStr | Ability of MultiColor scanning laser ophthalmoscope to detect non-glaucomatous retinal nerve fiber layer defects in eyes with retinal diseases |
| title_full_unstemmed | Ability of MultiColor scanning laser ophthalmoscope to detect non-glaucomatous retinal nerve fiber layer defects in eyes with retinal diseases |
| title_short | Ability of MultiColor scanning laser ophthalmoscope to detect non-glaucomatous retinal nerve fiber layer defects in eyes with retinal diseases |
| title_sort | ability of multicolor scanning laser ophthalmoscope to detect non glaucomatous retinal nerve fiber layer defects in eyes with retinal diseases |
| topic | Non-glaucomatous NFLD Scanning laser ophthalmoscope Spectralis MultiColor |
| url | http://link.springer.com/article/10.1186/s12886-018-0995-8 |
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