Host Subcellular Organelles: Targets of Viral Manipulation
Viruses have evolved sophisticated mechanisms to manipulate host cell processes and utilize intracellular organelles to facilitate their replication. These complex interactions between viruses and cellular organelles allow them to hijack the cellular machinery and impair homeostasis. Moreover, viral...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/25/3/1638 |
| _version_ | 1797318692152803328 |
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| author | Min Seok Song Dong-Kun Lee Chung-Young Lee Sang-Cheol Park Jinsung Yang |
| author_facet | Min Seok Song Dong-Kun Lee Chung-Young Lee Sang-Cheol Park Jinsung Yang |
| author_sort | Min Seok Song |
| collection | DOAJ |
| description | Viruses have evolved sophisticated mechanisms to manipulate host cell processes and utilize intracellular organelles to facilitate their replication. These complex interactions between viruses and cellular organelles allow them to hijack the cellular machinery and impair homeostasis. Moreover, viral infection alters the cell membrane’s structure and composition and induces vesicle formation to facilitate intracellular trafficking of viral components. However, the research focus has predominantly been on the immune response elicited by viruses, often overlooking the significant alterations that viruses induce in cellular organelles. Gaining a deeper understanding of these virus-induced cellular changes is crucial for elucidating the full life cycle of viruses and developing potent antiviral therapies. Exploring virus-induced cellular changes could substantially improve our understanding of viral infection mechanisms. |
| first_indexed | 2024-03-08T03:55:57Z |
| format | Article |
| id | doaj.art-c2bf5c69ea0e4158b4fd511bf279aef4 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-08T03:55:57Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-c2bf5c69ea0e4158b4fd511bf279aef42024-02-09T15:14:01ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672024-01-01253163810.3390/ijms25031638Host Subcellular Organelles: Targets of Viral ManipulationMin Seok Song0Dong-Kun Lee1Chung-Young Lee2Sang-Cheol Park3Jinsung Yang4Department of Physiology and Convergence Medical Science, Institute of Medical Science, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of KoreaDepartment of Physiology and Convergence Medical Science, Institute of Medical Science, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of KoreaDepartment of Microbiology, School of Medicine, Kyungpook National University, Daegu 41944, Republic of KoreaArtificial Intelligence and Robotics Laboratory, Myongji Hospital, Goyang 10475, Republic of KoreaDepartment of Biochemistry and Convergence Medical Science, Institute of Medical Science, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of KoreaViruses have evolved sophisticated mechanisms to manipulate host cell processes and utilize intracellular organelles to facilitate their replication. These complex interactions between viruses and cellular organelles allow them to hijack the cellular machinery and impair homeostasis. Moreover, viral infection alters the cell membrane’s structure and composition and induces vesicle formation to facilitate intracellular trafficking of viral components. However, the research focus has predominantly been on the immune response elicited by viruses, often overlooking the significant alterations that viruses induce in cellular organelles. Gaining a deeper understanding of these virus-induced cellular changes is crucial for elucidating the full life cycle of viruses and developing potent antiviral therapies. Exploring virus-induced cellular changes could substantially improve our understanding of viral infection mechanisms.https://www.mdpi.com/1422-0067/25/3/1638virusinfectionorganellesendoplasmic reticulummembraneendocytosis |
| spellingShingle | Min Seok Song Dong-Kun Lee Chung-Young Lee Sang-Cheol Park Jinsung Yang Host Subcellular Organelles: Targets of Viral Manipulation International Journal of Molecular Sciences virus infection organelles endoplasmic reticulum membrane endocytosis |
| title | Host Subcellular Organelles: Targets of Viral Manipulation |
| title_full | Host Subcellular Organelles: Targets of Viral Manipulation |
| title_fullStr | Host Subcellular Organelles: Targets of Viral Manipulation |
| title_full_unstemmed | Host Subcellular Organelles: Targets of Viral Manipulation |
| title_short | Host Subcellular Organelles: Targets of Viral Manipulation |
| title_sort | host subcellular organelles targets of viral manipulation |
| topic | virus infection organelles endoplasmic reticulum membrane endocytosis |
| url | https://www.mdpi.com/1422-0067/25/3/1638 |
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