Sinonasal Meningioma in a Siberian Tiger (<i>Panthera tigris altaica</i>)
Meningiomas are the most common primary brain tumour in dogs and cats. However, whilst there are numerous reports of extracranial (spinal, orbital and sinonasal) meningiomas in the dog, there have only been a few case reports of spinal meningiomas, and no post-mortem confirmed orbital or sinonasal m...
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| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/9/9/457 |
| _version_ | 1797481510219022336 |
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| author | Louise van der Weyden Peter Caldwell Christine Steyrer Nicolize O’Dell Alischa Henning |
| author_facet | Louise van der Weyden Peter Caldwell Christine Steyrer Nicolize O’Dell Alischa Henning |
| author_sort | Louise van der Weyden |
| collection | DOAJ |
| description | Meningiomas are the most common primary brain tumour in dogs and cats. However, whilst there are numerous reports of extracranial (spinal, orbital and sinonasal) meningiomas in the dog, there have only been a few case reports of spinal meningiomas, and no post-mortem confirmed orbital or sinonasal meningiomas in cats. In this report, a 20-year-old captive tiger (<i>Panthera tigris altaica</i>) with a history of chronic ocular inflammation resulting in enucleation, spontaneously developed tetanic convulsions (epileptic seizures) that over a 2-year period resulted in a gradually worsening condition and the animal was eventually euthanized. At autopsy, a focal, expansile, neoplastic mass was found in the caudal nasal cavity midline, abutting the cribriform plate and slightly compressing the calvarium. Histological analysis revealed nasal turbinates attached to a well-circumscribed expansile multi-lobular mass consisting of interlacing whorls and streams of neoplastic cells supported by a variably fibrous to microcystic collagenous matrix displaying rare psammoma bodies. The diagnosis was sinonasal transitional meningioma. This is the first report of a captive wild felid with an extracranial meningioma, specifically a tiger with a sinonasal transitional meningioma. |
| first_indexed | 2024-03-09T22:15:39Z |
| format | Article |
| id | doaj.art-c2c2997f7caf4d6cb50d0f5d97aebf17 |
| institution | Directory Open Access Journal |
| issn | 2306-7381 |
| language | English |
| last_indexed | 2024-03-09T22:15:39Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj.art-c2c2997f7caf4d6cb50d0f5d97aebf172023-11-23T19:23:42ZengMDPI AGVeterinary Sciences2306-73812022-08-019945710.3390/vetsci9090457Sinonasal Meningioma in a Siberian Tiger (<i>Panthera tigris altaica</i>)Louise van der Weyden0Peter Caldwell1Christine Steyrer2Nicolize O’Dell3Alischa Henning4Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge CB10 1SA, UKOld Chapel Veterinary Clinic, Villieria, Pretoria 0186, South AfricaLionsrock Big Cat Sanctuary, Bethlehem 9700, South AfricaDepartment of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Onderstepoort 0110, South AfricaDepartment of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Onderstepoort 0110, South AfricaMeningiomas are the most common primary brain tumour in dogs and cats. However, whilst there are numerous reports of extracranial (spinal, orbital and sinonasal) meningiomas in the dog, there have only been a few case reports of spinal meningiomas, and no post-mortem confirmed orbital or sinonasal meningiomas in cats. In this report, a 20-year-old captive tiger (<i>Panthera tigris altaica</i>) with a history of chronic ocular inflammation resulting in enucleation, spontaneously developed tetanic convulsions (epileptic seizures) that over a 2-year period resulted in a gradually worsening condition and the animal was eventually euthanized. At autopsy, a focal, expansile, neoplastic mass was found in the caudal nasal cavity midline, abutting the cribriform plate and slightly compressing the calvarium. Histological analysis revealed nasal turbinates attached to a well-circumscribed expansile multi-lobular mass consisting of interlacing whorls and streams of neoplastic cells supported by a variably fibrous to microcystic collagenous matrix displaying rare psammoma bodies. The diagnosis was sinonasal transitional meningioma. This is the first report of a captive wild felid with an extracranial meningioma, specifically a tiger with a sinonasal transitional meningioma.https://www.mdpi.com/2306-7381/9/9/457tigertumourmeningiomatransitionalsinonasal |
| spellingShingle | Louise van der Weyden Peter Caldwell Christine Steyrer Nicolize O’Dell Alischa Henning Sinonasal Meningioma in a Siberian Tiger (<i>Panthera tigris altaica</i>) Veterinary Sciences tiger tumour meningioma transitional sinonasal |
| title | Sinonasal Meningioma in a Siberian Tiger (<i>Panthera tigris altaica</i>) |
| title_full | Sinonasal Meningioma in a Siberian Tiger (<i>Panthera tigris altaica</i>) |
| title_fullStr | Sinonasal Meningioma in a Siberian Tiger (<i>Panthera tigris altaica</i>) |
| title_full_unstemmed | Sinonasal Meningioma in a Siberian Tiger (<i>Panthera tigris altaica</i>) |
| title_short | Sinonasal Meningioma in a Siberian Tiger (<i>Panthera tigris altaica</i>) |
| title_sort | sinonasal meningioma in a siberian tiger i panthera tigris altaica i |
| topic | tiger tumour meningioma transitional sinonasal |
| url | https://www.mdpi.com/2306-7381/9/9/457 |
| work_keys_str_mv | AT louisevanderweyden sinonasalmeningiomainasiberiantigeripantheratigrisaltaicai AT petercaldwell sinonasalmeningiomainasiberiantigeripantheratigrisaltaicai AT christinesteyrer sinonasalmeningiomainasiberiantigeripantheratigrisaltaicai AT nicolizeodell sinonasalmeningiomainasiberiantigeripantheratigrisaltaicai AT alischahenning sinonasalmeningiomainasiberiantigeripantheratigrisaltaicai |