Catastrophic antiphospholipid syndrome. Pathogenesis issues
Сatastrophic antiphospholipid syndrome (CAPS) is an uncommon, often fatal, variant of the antiphospholipid syndrome that results in a widespread coagulopathy and high titres os antiphospholipid antibodies and affects predominantly small vessels supplying organs with the development of multiorgan fai...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | Russian |
Published: |
IRBIS LLC
2016-06-01
|
Series: | Акушерство, гинекология и репродукция |
Subjects: | |
Online Access: | https://www.gynecology.su/jour/article/view/156 |
_version_ | 1797884231047708672 |
---|---|
author | V. O. Bitsadze D. K. Khizroeva L. E. Idrisova R. R. Abramyan M. D. Andreeva A. D. Makatsariya |
author_facet | V. O. Bitsadze D. K. Khizroeva L. E. Idrisova R. R. Abramyan M. D. Andreeva A. D. Makatsariya |
author_sort | V. O. Bitsadze |
collection | DOAJ |
description | Сatastrophic antiphospholipid syndrome (CAPS) is an uncommon, often fatal, variant of the antiphospholipid syndrome that results in a widespread coagulopathy and high titres os antiphospholipid antibodies and affects predominantly small vessels supplying organs with the development of multiorgan failure. International approaches on terminology, risk factors, pathogenesis, criteria of diagnostics, clinical symptoms and management of patients with CAPS are reviewed. Own clinical experience of management 17 patients with CAPS development also presented. CAPS is life-threatening condition but optimal treatment for CAPS is not developed yet. CAPS presents a multidisciplinary problem. |
first_indexed | 2024-04-10T04:03:02Z |
format | Article |
id | doaj.art-c2c2a691338745b6b9ccdf48b644791a |
institution | Directory Open Access Journal |
issn | 2313-7347 2500-3194 |
language | Russian |
last_indexed | 2024-04-10T04:03:02Z |
publishDate | 2016-06-01 |
publisher | IRBIS LLC |
record_format | Article |
series | Акушерство, гинекология и репродукция |
spelling | doaj.art-c2c2a691338745b6b9ccdf48b644791a2023-03-13T07:09:46ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942016-06-0192325310.17749/2070-4968.2015.9.2.032-053154Catastrophic antiphospholipid syndrome. Pathogenesis issuesV. O. Bitsadze0D. K. Khizroeva1L. E. Idrisova2R. R. Abramyan3M. D. Andreeva4A. D. Makatsariya5First Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationKuban State Medical University of the Russian Health Ministry, KrasnodarFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationСatastrophic antiphospholipid syndrome (CAPS) is an uncommon, often fatal, variant of the antiphospholipid syndrome that results in a widespread coagulopathy and high titres os antiphospholipid antibodies and affects predominantly small vessels supplying organs with the development of multiorgan failure. International approaches on terminology, risk factors, pathogenesis, criteria of diagnostics, clinical symptoms and management of patients with CAPS are reviewed. Own clinical experience of management 17 patients with CAPS development also presented. CAPS is life-threatening condition but optimal treatment for CAPS is not developed yet. CAPS presents a multidisciplinary problem.https://www.gynecology.su/jour/article/view/156antiphospholipid syndromerare diseasethrombotic stormcatastrophic aps |
spellingShingle | V. O. Bitsadze D. K. Khizroeva L. E. Idrisova R. R. Abramyan M. D. Andreeva A. D. Makatsariya Catastrophic antiphospholipid syndrome. Pathogenesis issues Акушерство, гинекология и репродукция antiphospholipid syndrome rare disease thrombotic storm catastrophic aps |
title | Catastrophic antiphospholipid syndrome. Pathogenesis issues |
title_full | Catastrophic antiphospholipid syndrome. Pathogenesis issues |
title_fullStr | Catastrophic antiphospholipid syndrome. Pathogenesis issues |
title_full_unstemmed | Catastrophic antiphospholipid syndrome. Pathogenesis issues |
title_short | Catastrophic antiphospholipid syndrome. Pathogenesis issues |
title_sort | catastrophic antiphospholipid syndrome pathogenesis issues |
topic | antiphospholipid syndrome rare disease thrombotic storm catastrophic aps |
url | https://www.gynecology.su/jour/article/view/156 |
work_keys_str_mv | AT vobitsadze catastrophicantiphospholipidsyndromepathogenesisissues AT dkkhizroeva catastrophicantiphospholipidsyndromepathogenesisissues AT leidrisova catastrophicantiphospholipidsyndromepathogenesisissues AT rrabramyan catastrophicantiphospholipidsyndromepathogenesisissues AT mdandreeva catastrophicantiphospholipidsyndromepathogenesisissues AT admakatsariya catastrophicantiphospholipidsyndromepathogenesisissues |