Targeting the Endocannabinoid/CB1 Receptor System For Treating Major Depression Through Antidepressant Activities of Curcumin and Dexanabinol-Loaded Solid Lipid Nanoparticles

Targeting the Endocannabinoid/CB1 Receptor System For Treating Major Depression Through Antidepressant Activities of Curcumin and Dexanabinol-Loaded Solid Lipid Nanoparticles

Background/Aims: This study investigated the underlying mechanisms of the antidepressant effects of curcumin and dexanabinol-loaded solid lipid nanoparticles in corticosterone-induced cell and mice depression models. Methods: Curcumin and dexanabinol-loaded solid lipid nanoparticles (Cur/SLNs-HU-211...

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Bibliographic Details
Main Authors: Xiaolie He, Li Yang, Mei Wang, Xizhen Zhuang, Ruiqi Huang, Rongrong Zhu, Shilong Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Rimonabant
CB1
Dexanabinol
Solid lipid nanoparticles
Major depression
Curcumin
Online Access:http://www.karger.com/Article/FullText/480001

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