Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy

<p>Abstract</p> <p>Background</p> <p>The Down syndrome phenotype has been attributed to overexpression of chromosome 21 (Hsa21) genes. However, the expression profile of Hsa21 genes in trisomic human subjects as well as their effects on genes located on different chromo...

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Bibliographic Details
Main Authors: Olla Carlo, D'Armiento Maria, Genesio Rita, Greco Dario, Negri Rosa, D'Agostino Paola, Fabbrini Floriana, Conti Anna, Paladini Dario, Zannini Mariastella, Nitsch Lucio
Format: Article
Language:English
Published: BMC 2007-08-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/8/268