Prefronto-striatal physiology is associated with schizotypy and is modulated by a functional variant of DRD2

Prefronto-striatal physiology is associated with schizotypy and is modulated by a functional variant of DRD2

Schizotypy is a latent organization of personality related to the genetic risk for schizophrenia. Some evidence suggests that schizophrenia and schizotypy share some biological features, including a link to dopaminergic D2 receptor signaling. A polymorphism in the D2 gene (DRD2 rs1076560, G>T) ha...

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Bibliographic Details
Main Authors: Paolo eTaurisano, Raffaella eRomano, Marina eMancini, Annabella eDi Giorgio, Linda Antonella Antonucci, Leonardo eFazio, Antonio eRampino, Tiziana eQuarto, Barbara eGelao, Annamaria ePorcelli, Apostolos ePapazacharias, Gianluca eUrsini, Grazia eCaforio, Rita eMasellis, Artor eNiccoli Asabella, Orlando eTodarello, Teresa ePopolizio, Giuseppe eRubini, Giuseppe eBlasi, Alessandro eBertolino
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Dopamine
fMRI
SPECT
DRD2
schizotypy
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00235/full

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