The role of oxidative stress in pediatric urinary tract infections: a systematic review
Introduction: Urinary tract infection (UTI) that can affect any part of the urinary tract and may subsequently lead to kidney infection is linked with variety of causative factors such as oxidative stress. In this study, we aimed to systematically review the literatures to evaluate the effects of ox...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2016-01-01
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| Series: | Reviews in Clinical Medicine |
| Subjects: | |
| Online Access: | https://rcm.mums.ac.ir/article_6374_e1d7fde8f3b97a6b9bbf35a2c2571242.pdf |
| _version_ | 1828085824118325248 |
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| author | Mostafa Delshad Azita Fesharakinia Samaneh Eghbal |
| author_facet | Mostafa Delshad Azita Fesharakinia Samaneh Eghbal |
| author_sort | Mostafa Delshad |
| collection | DOAJ |
| description | Introduction: Urinary tract infection (UTI) that can affect any part of the urinary tract and may subsequently lead to kidney infection is linked with variety of causative factors such as oxidative stress. In this study, we aimed to systematically review the literatures to evaluate the effects of oxidative stress on UTI. Method: PubMed and Google scholar were searched systematically using the key terms, “oxidative stress” and “urinary tract infection” in the title, keywords, and abstract on February 2015 to find articles in which the oxidative stresses had been evaluated in children with urinary tract infection (UTI). Papers were excluded if they were unrelated to the purpose of this study, or in language other than English. Full texts of the relevant documents were fully reviewed for data extraction.Result: Of overall 50 articles from PubMed, and 6 records found in Google scholar, only 8 articles met the inclusion criteria for further assessment. Additionally, three papers were omitted due to full texts unavailability or language irrelevancy, and five articles, which fully met the inclusion criteria, were used for data extraction. The results showed that the level of antioxidant decreases significantly in patients with UTI, while the markers of oxidative stress increases.Conclusions: The results of the studies showed that the level of antioxidants decreases in patients with UTI, while lipid peroxidase and the level of oxidative stress biomarkers such as malondialdehyde and reactive oxygen species increase. These findings are suggestive of an association between oxidative stress and UTI. The role of oxidative stress in pediatric urinary tract infections: a systematic review |
| first_indexed | 2024-04-11T04:45:57Z |
| format | Article |
| id | doaj.art-c2cf4b4b85864d7a96a9ec12561397a9 |
| institution | Directory Open Access Journal |
| issn | 2345-6256 2345-6892 |
| language | English |
| last_indexed | 2024-04-11T04:45:57Z |
| publishDate | 2016-01-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Reviews in Clinical Medicine |
| spelling | doaj.art-c2cf4b4b85864d7a96a9ec12561397a92022-12-27T13:10:47ZengMashhad University of Medical SciencesReviews in Clinical Medicine2345-62562345-68922016-01-0131434710.17463/RCM.2016.01.0106374The role of oxidative stress in pediatric urinary tract infections: a systematic reviewMostafa Delshad0Azita Fesharakinia1Samaneh Eghbal2Department of Anesthesiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Pediatric, Valiasr Hospital, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran.Department of Pediatric, Valiasr Hospital, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran.Introduction: Urinary tract infection (UTI) that can affect any part of the urinary tract and may subsequently lead to kidney infection is linked with variety of causative factors such as oxidative stress. In this study, we aimed to systematically review the literatures to evaluate the effects of oxidative stress on UTI. Method: PubMed and Google scholar were searched systematically using the key terms, “oxidative stress” and “urinary tract infection” in the title, keywords, and abstract on February 2015 to find articles in which the oxidative stresses had been evaluated in children with urinary tract infection (UTI). Papers were excluded if they were unrelated to the purpose of this study, or in language other than English. Full texts of the relevant documents were fully reviewed for data extraction.Result: Of overall 50 articles from PubMed, and 6 records found in Google scholar, only 8 articles met the inclusion criteria for further assessment. Additionally, three papers were omitted due to full texts unavailability or language irrelevancy, and five articles, which fully met the inclusion criteria, were used for data extraction. The results showed that the level of antioxidant decreases significantly in patients with UTI, while the markers of oxidative stress increases.Conclusions: The results of the studies showed that the level of antioxidants decreases in patients with UTI, while lipid peroxidase and the level of oxidative stress biomarkers such as malondialdehyde and reactive oxygen species increase. These findings are suggestive of an association between oxidative stress and UTI. The role of oxidative stress in pediatric urinary tract infections: a systematic reviewhttps://rcm.mums.ac.ir/article_6374_e1d7fde8f3b97a6b9bbf35a2c2571242.pdfantioxidantsoxidative stressurinary tract infection |
| spellingShingle | Mostafa Delshad Azita Fesharakinia Samaneh Eghbal The role of oxidative stress in pediatric urinary tract infections: a systematic review Reviews in Clinical Medicine antioxidants oxidative stress urinary tract infection |
| title | The role of oxidative stress in pediatric urinary tract infections: a systematic review |
| title_full | The role of oxidative stress in pediatric urinary tract infections: a systematic review |
| title_fullStr | The role of oxidative stress in pediatric urinary tract infections: a systematic review |
| title_full_unstemmed | The role of oxidative stress in pediatric urinary tract infections: a systematic review |
| title_short | The role of oxidative stress in pediatric urinary tract infections: a systematic review |
| title_sort | role of oxidative stress in pediatric urinary tract infections a systematic review |
| topic | antioxidants oxidative stress urinary tract infection |
| url | https://rcm.mums.ac.ir/article_6374_e1d7fde8f3b97a6b9bbf35a2c2571242.pdf |
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