A scoping review of health-related stigma outcomes for high-burden diseases in low- and middle-income countries

Abstract Background Stigma is associated with health conditions that drive disease burden in low- and middle-income countries (LMICs), including HIV, tuberculosis, mental health problems, epilepsy, and substance use disorders. However, the literature discussing the relationship between stigma and he...

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Main Authors: Jeremy C. Kane, Melissa A. Elafros, Sarah M. Murray, Ellen M. H. Mitchell, Jura L. Augustinavicius, Sara Causevic, Stefan D. Baral
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12916-019-1250-8
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author Jeremy C. Kane
Melissa A. Elafros
Sarah M. Murray
Ellen M. H. Mitchell
Jura L. Augustinavicius
Sara Causevic
Stefan D. Baral
author_facet Jeremy C. Kane
Melissa A. Elafros
Sarah M. Murray
Ellen M. H. Mitchell
Jura L. Augustinavicius
Sara Causevic
Stefan D. Baral
author_sort Jeremy C. Kane
collection DOAJ
description Abstract Background Stigma is associated with health conditions that drive disease burden in low- and middle-income countries (LMICs), including HIV, tuberculosis, mental health problems, epilepsy, and substance use disorders. However, the literature discussing the relationship between stigma and health outcomes is largely fragmented within disease-specific siloes, thus limiting the identification of common moderators or mechanisms through which stigma potentiates adverse health outcomes as well as the development of broadly relevant stigma mitigation interventions. Methods We conducted a scoping review to provide a critical overview of the breadth of research on stigma for each of the five aforementioned conditions in LMICs, including their methodological strengths and limitations. Results Across the range of diseases and disorders studied, stigma is associated with poor health outcomes, including help- and treatment-seeking behaviors. Common methodological limitations include a lack of prospective studies, non-representative samples resulting in limited generalizability, and a dearth of data on mediators and moderators of the relationship between stigma and health outcomes. Conclusions Implementing effective stigma mitigation interventions at scale necessitates transdisciplinary longitudinal studies that examine how stigma potentiates the risk for adverse outcomes for high-burden health conditions in community-based samples in LMICs.
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spelling doaj.art-c2d08953edf2404fa92e7c3c443c2e352022-12-22T03:04:36ZengBMCBMC Medicine1741-70152019-02-0117114010.1186/s12916-019-1250-8A scoping review of health-related stigma outcomes for high-burden diseases in low- and middle-income countriesJeremy C. Kane0Melissa A. Elafros1Sarah M. Murray2Ellen M. H. Mitchell3Jura L. Augustinavicius4Sara Causevic5Stefan D. Baral6Department of Mental Health, Johns Hopkins Bloomberg School of Public HealthDepartment of Neurology, Johns Hopkins School of MedicineDepartment of Mental Health, Johns Hopkins Bloomberg School of Public HealthInternational Institute for Social Studies, Erasmus UniversityDepartment of Mental Health, Johns Hopkins Bloomberg School of Public HealthDepartment of Public Health Sciences, Karolinska Institutet, Widerströmska husetDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public HealthAbstract Background Stigma is associated with health conditions that drive disease burden in low- and middle-income countries (LMICs), including HIV, tuberculosis, mental health problems, epilepsy, and substance use disorders. However, the literature discussing the relationship between stigma and health outcomes is largely fragmented within disease-specific siloes, thus limiting the identification of common moderators or mechanisms through which stigma potentiates adverse health outcomes as well as the development of broadly relevant stigma mitigation interventions. Methods We conducted a scoping review to provide a critical overview of the breadth of research on stigma for each of the five aforementioned conditions in LMICs, including their methodological strengths and limitations. Results Across the range of diseases and disorders studied, stigma is associated with poor health outcomes, including help- and treatment-seeking behaviors. Common methodological limitations include a lack of prospective studies, non-representative samples resulting in limited generalizability, and a dearth of data on mediators and moderators of the relationship between stigma and health outcomes. Conclusions Implementing effective stigma mitigation interventions at scale necessitates transdisciplinary longitudinal studies that examine how stigma potentiates the risk for adverse outcomes for high-burden health conditions in community-based samples in LMICs.http://link.springer.com/article/10.1186/s12916-019-1250-8StigmaLow- and middle-income countriesHIVTuberculosisEpilepsyDepression
spellingShingle Jeremy C. Kane
Melissa A. Elafros
Sarah M. Murray
Ellen M. H. Mitchell
Jura L. Augustinavicius
Sara Causevic
Stefan D. Baral
A scoping review of health-related stigma outcomes for high-burden diseases in low- and middle-income countries
BMC Medicine
Stigma
Low- and middle-income countries
HIV
Tuberculosis
Epilepsy
Depression
title A scoping review of health-related stigma outcomes for high-burden diseases in low- and middle-income countries
title_full A scoping review of health-related stigma outcomes for high-burden diseases in low- and middle-income countries
title_fullStr A scoping review of health-related stigma outcomes for high-burden diseases in low- and middle-income countries
title_full_unstemmed A scoping review of health-related stigma outcomes for high-burden diseases in low- and middle-income countries
title_short A scoping review of health-related stigma outcomes for high-burden diseases in low- and middle-income countries
title_sort scoping review of health related stigma outcomes for high burden diseases in low and middle income countries
topic Stigma
Low- and middle-income countries
HIV
Tuberculosis
Epilepsy
Depression
url http://link.springer.com/article/10.1186/s12916-019-1250-8
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