Evidence for close molecular proximity between reverting and undifferentiated cells

Evidence for close molecular proximity between reverting and undifferentiated cells

Abstract Background According to Waddington’s epigenetic landscape concept, the differentiation process can be illustrated by a cell akin to a ball rolling down from the top of a hill (proliferation state) and crossing furrows before stopping in basins or “attractor states” to reach its stable diffe...

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Bibliographic Details
Main Authors: Souad Zreika, Camille Fourneaux, Elodie Vallin, Laurent Modolo, Rémi Seraphin, Alice Moussy, Elias Ventre, Matteo Bouvier, Anthony Ozier-Lafontaine, Arnaud Bonnaffoux, Franck Picard, Olivier Gandrillon, Sandrine Gonin-Giraud
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Biology
Subjects:
Cell-fate reversion
Cell differentiation
Erythroid progenitors
Single-cell RNA-seq
Single-cell RT-qPCR
Online Access:https://doi.org/10.1186/s12915-022-01363-7

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