Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas)
BackgroundStroke is the second leading cause of death in Brazil. The social and financial burden of stroke is remarkable; however, the epidemiological profile remains poorly understood.ObjectiveThe aim of this study was to report the incidence, lethality, and functional status at 30 and 90 days post...
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.966785/full |
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| author | Emily dos Santos Giulia M. Wollmann Vivian Nagel Herminia M. S. Ponte Luis E. T. A. Furtado Rui K. V. Martins-Filho Gustavo Weiss Gustavo Weiss Sheila C. O. Martins Sheila C. O. Martins Leslie E. Ferreira Leslie E. Ferreira Paulo H. C. de França Paulo H. C. de França Norberto L. Cabral Norberto L. Cabral Norberto L. Cabral |
| author_facet | Emily dos Santos Giulia M. Wollmann Vivian Nagel Herminia M. S. Ponte Luis E. T. A. Furtado Rui K. V. Martins-Filho Gustavo Weiss Gustavo Weiss Sheila C. O. Martins Sheila C. O. Martins Leslie E. Ferreira Leslie E. Ferreira Paulo H. C. de França Paulo H. C. de França Norberto L. Cabral Norberto L. Cabral Norberto L. Cabral |
| author_sort | Emily dos Santos |
| collection | DOAJ |
| description | BackgroundStroke is the second leading cause of death in Brazil. The social and financial burden of stroke is remarkable; however, the epidemiological profile remains poorly understood.ObjectiveThe aim of this study was to report the incidence, lethality, and functional status at 30 and 90 days post-stroke in the cities of different Brazilian macro-regions.MethodsThis is an observational, prospective, and population-based study, led in Canoas (South), Joinville (South, reference center), Sertãozinho (Southeast), and Sobral (Northeast) in Brazil. It was developed according to the three-step criteria recommended by the World Health Organization to conduct population-based studies on stroke. Using different sources, all hospitalized and ambulatory patients with stroke were identified and the same criteria were kept in all cities. All first events were included, regardless of sex, age, or type of stroke. Demographic and risk factor data were collected, followed by biochemical, electrocardiographic, and radiological test results. Functional status and lethality were obtained using the mRankin scale through telephonic interview (validated Brazilian version).ResultsIn 1 year, 932 stroke cases were registered (784 ischemic stroke, 105 hemorrhagic stroke, and 43 subarachnoid hemorrhage). The incidence rates per 100,000 inhabitants, adjusted for the world population, were 63 in Canoas, 106 in Joinville, 72 in Sertãozinho, and 96 in Sobral. The majority (70.8%) were followed for 90 days. Kaplan–Meier curves showed that 90-day survival was different among cities. Sobral, which has the lowest socioeconomic indexes, revealed the worst results in terms of lethality and functional status.ConclusionThis study expands the knowledge of stroke epidemiology in Brazil, a middle-income country with enormous socioeconomic and cultural diversity. The discrepancy observed regarding the impact of stroke in patients from Joinville and Sobral highlights the need to improve the strategic allocation of resources to meet the health priorities in each location. |
| first_indexed | 2024-12-10T10:49:27Z |
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| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-12-10T10:49:27Z |
| publishDate | 2022-09-01 |
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| series | Frontiers in Neurology |
| spelling | doaj.art-c2d12fb768a54ea387b0c6da6faed3f72022-12-22T01:52:04ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-09-011310.3389/fneur.2022.966785966785Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas)Emily dos Santos0Giulia M. Wollmann1Vivian Nagel2Herminia M. S. Ponte3Luis E. T. A. Furtado4Rui K. V. Martins-Filho5Gustavo Weiss6Gustavo Weiss7Sheila C. O. Martins8Sheila C. O. Martins9Leslie E. Ferreira10Leslie E. Ferreira11Paulo H. C. de França12Paulo H. C. de França13Norberto L. Cabral14Norberto L. Cabral15Norberto L. Cabral16Postgraduate Program on Health and Environment, University of the Region of Joinville–Univille, Joinville, BrazilDepartment of Medicine, University of the Region of Joinville–Univille, Joinville, BrazilJoinville Stroke Registry, Hospital Municipal São José, Joinville, BrazilDepartment of Nursing, Inta University Center–UNINTA, Sobral, BrazilDepartment of Clinical Medicine, Federal University of Ceará, Sobral, BrazilHospital das Clínicas de Ribeirão Preto, University of São Paulo–USP, Ribeirão Preto, BrazilHospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, BrazilHospital Moinhos de Vento, Porto Alegre, BrazilHospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, BrazilHospital Moinhos de Vento, Porto Alegre, BrazilPostgraduate Program on Health and Environment, University of the Region of Joinville–Univille, Joinville, BrazilDepartment of Medicine, University of the Region of Joinville–Univille, Joinville, BrazilPostgraduate Program on Health and Environment, University of the Region of Joinville–Univille, Joinville, BrazilDepartment of Medicine, University of the Region of Joinville–Univille, Joinville, BrazilPostgraduate Program on Health and Environment, University of the Region of Joinville–Univille, Joinville, BrazilDepartment of Medicine, University of the Region of Joinville–Univille, Joinville, BrazilJoinville Stroke Registry, Hospital Municipal São José, Joinville, BrazilBackgroundStroke is the second leading cause of death in Brazil. The social and financial burden of stroke is remarkable; however, the epidemiological profile remains poorly understood.ObjectiveThe aim of this study was to report the incidence, lethality, and functional status at 30 and 90 days post-stroke in the cities of different Brazilian macro-regions.MethodsThis is an observational, prospective, and population-based study, led in Canoas (South), Joinville (South, reference center), Sertãozinho (Southeast), and Sobral (Northeast) in Brazil. It was developed according to the three-step criteria recommended by the World Health Organization to conduct population-based studies on stroke. Using different sources, all hospitalized and ambulatory patients with stroke were identified and the same criteria were kept in all cities. All first events were included, regardless of sex, age, or type of stroke. Demographic and risk factor data were collected, followed by biochemical, electrocardiographic, and radiological test results. Functional status and lethality were obtained using the mRankin scale through telephonic interview (validated Brazilian version).ResultsIn 1 year, 932 stroke cases were registered (784 ischemic stroke, 105 hemorrhagic stroke, and 43 subarachnoid hemorrhage). The incidence rates per 100,000 inhabitants, adjusted for the world population, were 63 in Canoas, 106 in Joinville, 72 in Sertãozinho, and 96 in Sobral. The majority (70.8%) were followed for 90 days. Kaplan–Meier curves showed that 90-day survival was different among cities. Sobral, which has the lowest socioeconomic indexes, revealed the worst results in terms of lethality and functional status.ConclusionThis study expands the knowledge of stroke epidemiology in Brazil, a middle-income country with enormous socioeconomic and cultural diversity. The discrepancy observed regarding the impact of stroke in patients from Joinville and Sobral highlights the need to improve the strategic allocation of resources to meet the health priorities in each location.https://www.frontiersin.org/articles/10.3389/fneur.2022.966785/fullstrokeepidemiologyincidencelethalityfunctional status |
| spellingShingle | Emily dos Santos Giulia M. Wollmann Vivian Nagel Herminia M. S. Ponte Luis E. T. A. Furtado Rui K. V. Martins-Filho Gustavo Weiss Gustavo Weiss Sheila C. O. Martins Sheila C. O. Martins Leslie E. Ferreira Leslie E. Ferreira Paulo H. C. de França Paulo H. C. de França Norberto L. Cabral Norberto L. Cabral Norberto L. Cabral Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas) Frontiers in Neurology stroke epidemiology incidence lethality functional status |
| title | Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas) |
| title_full | Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas) |
| title_fullStr | Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas) |
| title_full_unstemmed | Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas) |
| title_short | Incidence, lethality, and post-stroke functional status in different Brazilian macro-regions: The SAMBA study (analysis of stroke in multiple Brazilian areas) |
| title_sort | incidence lethality and post stroke functional status in different brazilian macro regions the samba study analysis of stroke in multiple brazilian areas |
| topic | stroke epidemiology incidence lethality functional status |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.966785/full |
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