A young child with HIV and unsteady gait: A case report
Background: We would like to raise awareness about the toxicities related to the added excipients present in the oral solution of Liponavir/ritonavir in particular alcohol and propylene glycol. Case presentation: In this case report, we describe an 18 month-old child with a newly diagnosed HIV infec...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-01-01
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| Series: | IDCases |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250919302823 |
| Summary: | Background: We would like to raise awareness about the toxicities related to the added excipients present in the oral solution of Liponavir/ritonavir in particular alcohol and propylene glycol. Case presentation: In this case report, we describe an 18 month-old child with a newly diagnosed HIV infection on antiretroviral therapy (ART). She developed shortly after starting the ART unsteady gait and imbalance. Conclusions: The excipient-excipient interaction in Lopinavir/ritonavir may contribute to major toxicities not only in premature neonates and infants; but also in older children specifically from Asian ethnicity. Keywords: HIV, Lopinavir-ritonavir, Unsteady gait |
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| ISSN: | 2214-2509 |