A young child with HIV and unsteady gait: A case report
Background: We would like to raise awareness about the toxicities related to the added excipients present in the oral solution of Liponavir/ritonavir in particular alcohol and propylene glycol. Case presentation: In this case report, we describe an 18 month-old child with a newly diagnosed HIV infec...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-01-01
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| Series: | IDCases |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250919302823 |
| _version_ | 1818907207482212352 |
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| author | Nadine Yazbeck Yolla Youssef Rima Hanna-Wakim |
| author_facet | Nadine Yazbeck Yolla Youssef Rima Hanna-Wakim |
| author_sort | Nadine Yazbeck |
| collection | DOAJ |
| description | Background: We would like to raise awareness about the toxicities related to the added excipients present in the oral solution of Liponavir/ritonavir in particular alcohol and propylene glycol. Case presentation: In this case report, we describe an 18 month-old child with a newly diagnosed HIV infection on antiretroviral therapy (ART). She developed shortly after starting the ART unsteady gait and imbalance. Conclusions: The excipient-excipient interaction in Lopinavir/ritonavir may contribute to major toxicities not only in premature neonates and infants; but also in older children specifically from Asian ethnicity. Keywords: HIV, Lopinavir-ritonavir, Unsteady gait |
| first_indexed | 2024-12-19T21:51:27Z |
| format | Article |
| id | doaj.art-c2d1320faac244c68bb83a20adf324d0 |
| institution | Directory Open Access Journal |
| issn | 2214-2509 |
| language | English |
| last_indexed | 2024-12-19T21:51:27Z |
| publishDate | 2020-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj.art-c2d1320faac244c68bb83a20adf324d02022-12-21T20:04:24ZengElsevierIDCases2214-25092020-01-0119A young child with HIV and unsteady gait: A case reportNadine Yazbeck0Yolla Youssef1Rima Hanna-Wakim2Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut, LebanonDepartment of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut, Lebanon; Division of Pediatric Infectious Diseases, Department of Pediatrics and Adolescent Medicine, Lebanon; Center for Infectious Diseases Research, American University of Beirut Medical Center, Beirut, LebanonDepartment of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut, Lebanon; Division of Pediatric Infectious Diseases, Department of Pediatrics and Adolescent Medicine, Lebanon; Center for Infectious Diseases Research, American University of Beirut Medical Center, Beirut, Lebanon; Corresponding author at: American University of Beirut, Riad El Solh 110 72020, Beirut, Lebanon.Background: We would like to raise awareness about the toxicities related to the added excipients present in the oral solution of Liponavir/ritonavir in particular alcohol and propylene glycol. Case presentation: In this case report, we describe an 18 month-old child with a newly diagnosed HIV infection on antiretroviral therapy (ART). She developed shortly after starting the ART unsteady gait and imbalance. Conclusions: The excipient-excipient interaction in Lopinavir/ritonavir may contribute to major toxicities not only in premature neonates and infants; but also in older children specifically from Asian ethnicity. Keywords: HIV, Lopinavir-ritonavir, Unsteady gaithttp://www.sciencedirect.com/science/article/pii/S2214250919302823 |
| spellingShingle | Nadine Yazbeck Yolla Youssef Rima Hanna-Wakim A young child with HIV and unsteady gait: A case report IDCases |
| title | A young child with HIV and unsteady gait: A case report |
| title_full | A young child with HIV and unsteady gait: A case report |
| title_fullStr | A young child with HIV and unsteady gait: A case report |
| title_full_unstemmed | A young child with HIV and unsteady gait: A case report |
| title_short | A young child with HIV and unsteady gait: A case report |
| title_sort | young child with hiv and unsteady gait a case report |
| url | http://www.sciencedirect.com/science/article/pii/S2214250919302823 |
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