Novel insight into functions of ascorbate peroxidase in higher plants: More than a simple antioxidant enzyme
As plants are sessile organisms, they are inevitably exposed to a variety of environmental stimuli that trigger rapid changes in the generation and disposal of reactive oxygen species such as hydrogen peroxide (H2O2). A major H2O2 scavenging system in plant cells is the ascorbate-glutathione cycle,...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-08-01
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| Series: | Redox Biology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231723001908 |
| _version_ | 1797784923436744704 |
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| author | Shengchun Li |
| author_facet | Shengchun Li |
| author_sort | Shengchun Li |
| collection | DOAJ |
| description | As plants are sessile organisms, they are inevitably exposed to a variety of environmental stimuli that trigger rapid changes in the generation and disposal of reactive oxygen species such as hydrogen peroxide (H2O2). A major H2O2 scavenging system in plant cells is the ascorbate-glutathione cycle, in which ascorbate peroxidase (APX) catalyzes the conversion of H2O2 into water employing ascorbate as specific electron donor. In higher plants, distinct APX isoforms can occur in multiple subcellular compartments, including chloroplasts, mitochondria, and peroxisomes and the cytosol, to modulate organellar and cellular levels of H2O2. It is well established that APX plays crucial roles in protecting plant cells against diverse environmental stresses, as well as in plant growth and development. Apart from ascorbate, recently, APXs have been found to have a broader substrate specificity and possess chaperone activity, hence participating various biological processes. In this review, we describe the antioxidant properties of APXs and highlight their novel roles beyond ‘ascorbate peroxidases’. |
| first_indexed | 2024-03-13T00:46:47Z |
| format | Article |
| id | doaj.art-c2d5a85cbe15457cbd5ef8e5709b6647 |
| institution | Directory Open Access Journal |
| issn | 2213-2317 |
| language | English |
| last_indexed | 2024-03-13T00:46:47Z |
| publishDate | 2023-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Redox Biology |
| spelling | doaj.art-c2d5a85cbe15457cbd5ef8e5709b66472023-07-09T04:21:53ZengElsevierRedox Biology2213-23172023-08-0164102789Novel insight into functions of ascorbate peroxidase in higher plants: More than a simple antioxidant enzymeShengchun Li0State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, 430062, ChinaAs plants are sessile organisms, they are inevitably exposed to a variety of environmental stimuli that trigger rapid changes in the generation and disposal of reactive oxygen species such as hydrogen peroxide (H2O2). A major H2O2 scavenging system in plant cells is the ascorbate-glutathione cycle, in which ascorbate peroxidase (APX) catalyzes the conversion of H2O2 into water employing ascorbate as specific electron donor. In higher plants, distinct APX isoforms can occur in multiple subcellular compartments, including chloroplasts, mitochondria, and peroxisomes and the cytosol, to modulate organellar and cellular levels of H2O2. It is well established that APX plays crucial roles in protecting plant cells against diverse environmental stresses, as well as in plant growth and development. Apart from ascorbate, recently, APXs have been found to have a broader substrate specificity and possess chaperone activity, hence participating various biological processes. In this review, we describe the antioxidant properties of APXs and highlight their novel roles beyond ‘ascorbate peroxidases’.http://www.sciencedirect.com/science/article/pii/S2213231723001908APXH2O2Antioxidant activitySubstrateChaperone |
| spellingShingle | Shengchun Li Novel insight into functions of ascorbate peroxidase in higher plants: More than a simple antioxidant enzyme Redox Biology APX H2O2 Antioxidant activity Substrate Chaperone |
| title | Novel insight into functions of ascorbate peroxidase in higher plants: More than a simple antioxidant enzyme |
| title_full | Novel insight into functions of ascorbate peroxidase in higher plants: More than a simple antioxidant enzyme |
| title_fullStr | Novel insight into functions of ascorbate peroxidase in higher plants: More than a simple antioxidant enzyme |
| title_full_unstemmed | Novel insight into functions of ascorbate peroxidase in higher plants: More than a simple antioxidant enzyme |
| title_short | Novel insight into functions of ascorbate peroxidase in higher plants: More than a simple antioxidant enzyme |
| title_sort | novel insight into functions of ascorbate peroxidase in higher plants more than a simple antioxidant enzyme |
| topic | APX H2O2 Antioxidant activity Substrate Chaperone |
| url | http://www.sciencedirect.com/science/article/pii/S2213231723001908 |
| work_keys_str_mv | AT shengchunli novelinsightintofunctionsofascorbateperoxidaseinhigherplantsmorethanasimpleantioxidantenzyme |