High Level of Soluble CD146 In Cerebrospinal Fluid Might be a Biomarker of Severity of Anti-N-Methyl-D-Aspartate Receptor Encephalitis

High Level of Soluble CD146 In Cerebrospinal Fluid Might be a Biomarker of Severity of Anti-N-Methyl-D-Aspartate Receptor Encephalitis

BackgroundDisruption of the blood–brain barrier (BBB) is an important pathophysiological process of anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis. A recent multi-center study showed that soluble (s) CD146 is a potential biomarker for monitoring early BBB damage and central nervous sys...

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Bibliographic Details
Main Authors: Qing Li, Jinglong Chen, Mengzhuo Yin, Jun Zhao, Fuchang Lu, Zhanhang Wang, Xiaoqi Yu, Shuangyan Wang, Dong Zheng, Honghao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
anti-NMDAR encephalitis
soluble CD146
cerebrospinal fluid
blood–brain barrier
neurological damages
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.680424/full

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