The Maintenance of Telomere Length in CD28+ T Cells During T Lymphocyte Stimulation
Abstract Telomerase activity is not readily detected in resting human T lymphocytes, however upon antigen presentation, telomerase is transiently upregulated. Presently, it is not known if telomerase activation is necessary for the proliferation of T cells or for the maintenance of telomere lengths....
Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado: |
Nature Portfolio
2017-07-01
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Series: | Scientific Reports |
Acceso en liña: | https://doi.org/10.1038/s41598-017-05174-7 |