Regulation of the DLC3 tumor suppressor by a novel phosphoswitch

Regulation of the DLC3 tumor suppressor by a novel phosphoswitch

Summary: Deleted in liver cancer 3 (DLC3) is a Rho GTPase-activating protein (RhoGAP) that plays a crucial role in maintaining adherens junction integrity and coordinating polarized vesicle transport by modulating Rho activity at the plasma membrane and endomembranes. By employing bioinformatical se...

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Bibliographic Details
Main Authors: Yannick Frey, Cristiana Lungu, Florian Meyer, Franziskus Hauth, Daniel Hahn, Corinna Kersten, Vivien Heller, Mirita Franz-Wachtel, Boris Macek, Igor Barsukov, Monilola A. Olayioye
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:iScience
Subjects:
Molecular interaction
Cell biology
Proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224014287

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http://www.sciencedirect.com/science/article/pii/S2589004224014287

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