<i>Cistus albidus</i> L.—Review of a Traditional Mediterranean Medicinal Plant with Pharmacological Potential

<i>Cistus albidus</i> L. (Cistaceae) is a medicinal plant that has been used therapeutically since ancient times in the Mediterranean basin for its important pharmacological properties. The ability of <i>C. albidus</i> to produce large quantities of a wide range of natural me...

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Main Authors: Daniel Raus de Baviera, Antonio Ruiz-Canales, Enrique Barrajón-Catalán
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Plants
Subjects:
Online Access:https://www.mdpi.com/2223-7747/12/16/2988
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author Daniel Raus de Baviera
Antonio Ruiz-Canales
Enrique Barrajón-Catalán
author_facet Daniel Raus de Baviera
Antonio Ruiz-Canales
Enrique Barrajón-Catalán
author_sort Daniel Raus de Baviera
collection DOAJ
description <i>Cistus albidus</i> L. (Cistaceae) is a medicinal plant that has been used therapeutically since ancient times in the Mediterranean basin for its important pharmacological properties. The ability of <i>C. albidus</i> to produce large quantities of a wide range of natural metabolites makes it an attractive source of raw material. The main constituents with bioactive functions that exert pharmacological effects are terpenes and polyphenols, with more than 200 identified compounds. The purpose of this review is to offer a detailed account of the botanical, ethnological, phytochemical, and pharmacological characteristics of <i>C. albidus</i> with the aim of encouraging additional pharmaceutical investigations into the potential therapeutic benefits of this medicinal plant. This review was carried out using organized searches of the available literature up to July 2023. A detailed analysis of <i>C. albidus</i> confirms its traditional use as a medicinal plant. The outcome of several studies suggests a deeper involvement of certain polyphenols and terpenes in multiple mechanisms such as inflammation and pain, with a potential application focus on neurodegenerative diseases and disorders. Other diseases such as prostate cancer and leukemia have already been researched with promising results for this plant, for which no intoxication has been reported in humans.
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spelling doaj.art-c2ddead42cce4274a0e698394fd5a9032023-11-19T02:42:01ZengMDPI AGPlants2223-77472023-08-011216298810.3390/plants12162988<i>Cistus albidus</i> L.—Review of a Traditional Mediterranean Medicinal Plant with Pharmacological PotentialDaniel Raus de Baviera0Antonio Ruiz-Canales1Enrique Barrajón-Catalán2Department of Engineering, Area of Agroforestry, Miguel Hernández University, 03312 Orihuela, SpainDepartment of Engineering, Area of Agroforestry, Miguel Hernández University, 03312 Orihuela, SpainInstitute for Research, Development and Innovation in Health Biotechnology, Miguel Hernández University, 03202 Elche, Spain<i>Cistus albidus</i> L. (Cistaceae) is a medicinal plant that has been used therapeutically since ancient times in the Mediterranean basin for its important pharmacological properties. The ability of <i>C. albidus</i> to produce large quantities of a wide range of natural metabolites makes it an attractive source of raw material. The main constituents with bioactive functions that exert pharmacological effects are terpenes and polyphenols, with more than 200 identified compounds. The purpose of this review is to offer a detailed account of the botanical, ethnological, phytochemical, and pharmacological characteristics of <i>C. albidus</i> with the aim of encouraging additional pharmaceutical investigations into the potential therapeutic benefits of this medicinal plant. This review was carried out using organized searches of the available literature up to July 2023. A detailed analysis of <i>C. albidus</i> confirms its traditional use as a medicinal plant. The outcome of several studies suggests a deeper involvement of certain polyphenols and terpenes in multiple mechanisms such as inflammation and pain, with a potential application focus on neurodegenerative diseases and disorders. Other diseases such as prostate cancer and leukemia have already been researched with promising results for this plant, for which no intoxication has been reported in humans.https://www.mdpi.com/2223-7747/12/16/2988<i>Cistus albidus</i>phytochemistrypharmacologypolyphenolsterpenestraditional uses
spellingShingle Daniel Raus de Baviera
Antonio Ruiz-Canales
Enrique Barrajón-Catalán
<i>Cistus albidus</i> L.—Review of a Traditional Mediterranean Medicinal Plant with Pharmacological Potential
Plants
<i>Cistus albidus</i>
phytochemistry
pharmacology
polyphenols
terpenes
traditional uses
title <i>Cistus albidus</i> L.—Review of a Traditional Mediterranean Medicinal Plant with Pharmacological Potential
title_full <i>Cistus albidus</i> L.—Review of a Traditional Mediterranean Medicinal Plant with Pharmacological Potential
title_fullStr <i>Cistus albidus</i> L.—Review of a Traditional Mediterranean Medicinal Plant with Pharmacological Potential
title_full_unstemmed <i>Cistus albidus</i> L.—Review of a Traditional Mediterranean Medicinal Plant with Pharmacological Potential
title_short <i>Cistus albidus</i> L.—Review of a Traditional Mediterranean Medicinal Plant with Pharmacological Potential
title_sort i cistus albidus i l review of a traditional mediterranean medicinal plant with pharmacological potential
topic <i>Cistus albidus</i>
phytochemistry
pharmacology
polyphenols
terpenes
traditional uses
url https://www.mdpi.com/2223-7747/12/16/2988
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AT antonioruizcanales icistusalbidusilreviewofatraditionalmediterraneanmedicinalplantwithpharmacologicalpotential
AT enriquebarrajoncatalan icistusalbidusilreviewofatraditionalmediterraneanmedicinalplantwithpharmacologicalpotential