The Influence of an Eight-Week Cycloergometer-Based Cardiac Rehabilitation on Serum Antioxidant Status in Men with Coronary Heart Disease: A Prospective Study
<i>Background and objectives:</i> A body of evidence confirms the benefits of cardiac rehabilitation (CR) in coronary heart disease (CHD) patients, but it remains unclear whether it enhances the antioxidant potential. The aim of the study was to assess the influence of an eight-week aero...
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| Format: | Article |
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MDPI AG
2019-04-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1010-660X/55/4/111 |
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| author | Anna Gawron-Skarbek Jacek Chrzczanowicz Joanna Kostka Dariusz Nowak Wojciech Drygas Anna Jegier Tomasz Kostka |
| author_facet | Anna Gawron-Skarbek Jacek Chrzczanowicz Joanna Kostka Dariusz Nowak Wojciech Drygas Anna Jegier Tomasz Kostka |
| author_sort | Anna Gawron-Skarbek |
| collection | DOAJ |
| description | <i>Background and objectives:</i> A body of evidence confirms the benefits of cardiac rehabilitation (CR) in coronary heart disease (CHD) patients, but it remains unclear whether it enhances the antioxidant potential. The aim of the study was to assess the influence of an eight-week aerobic cycloergometer-based CR program on serum total antioxidant capacity (TAC) and other CHD risk factors. <i>Materials and Methods:</i> The study involved 36 men with CHD (55.2 ± 9.0 years). TAC was assessed with two methods: ferric reducing ability of serum (TAC-FRAS) and 2.2-diphenyl-1-picryl-hydrazyl (TAC-DPPH). Aerobic capacity was evaluated during a submaximal exercise test. TAC and other anthropometric, biochemical and physical activity/fitness measures were performed twice: before the beginning and after termination of CR. <i>Results:</i> Aerobic capacity was higher (7.0 ± 2.6 vs. 8.0 ± 2.5 MET—metabolic equivalents; <i>p</i> < 0.01), but values of resting diastolic blood pressure were lower (81.9 ± 7.6 vs. 77.4 ± 8.9 mmHg; <i>p</i> < 0.01) after termination of CR. Other classic cardiometabolic, anthropometric, and biochemical measures did not change with CR. No difference in TAC-FRAS was found after CR, whereas TAC-DPPH was significantly lower (16.4 ± 4.0 vs. 13.2 ± 3.7% reduction; <i>p</i> < 0.01). <i>Conclusions:</i> Antioxidant potential measured as TAC-DPPH, but not as TAC-FRAS, decreased with the CR program. The recognized health benefits of CR are not related to augmented serum antioxidant status. |
| first_indexed | 2024-03-12T08:44:13Z |
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| id | doaj.art-c2dfff2881cd4cc4946c2116536e706a |
| institution | Directory Open Access Journal |
| issn | 1010-660X |
| language | English |
| last_indexed | 2024-03-12T08:44:13Z |
| publishDate | 2019-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-c2dfff2881cd4cc4946c2116536e706a2023-09-02T16:33:34ZengMDPI AGMedicina1010-660X2019-04-0155411110.3390/medicina55040111medicina55040111The Influence of an Eight-Week Cycloergometer-Based Cardiac Rehabilitation on Serum Antioxidant Status in Men with Coronary Heart Disease: A Prospective StudyAnna Gawron-Skarbek0Jacek Chrzczanowicz1Joanna Kostka2Dariusz Nowak3Wojciech Drygas4Anna Jegier5Tomasz Kostka6Department of Hygiene and Health Promotion, Medical University of Lodz, 90-752 Lodz, PolandCardiac Rehabilitation Centre, Copernicus Memorial Hospital, Lodz, 90-001 Lodz, PolandDepartment of Physical Medicine, Medical University of Lodz, 90-647 Lodz, PolandDepartment of Clinical Physiology, Medical University of Lodz, 92-215 Lodz, PolandDepartment of Preventive Medicine, Medical University of Lodz, 90-752 Lodz, PolandDepartment of Sports Medicine, Medical University of Lodz, 92-213 Lodz, PolandDepartment of Geriatrics, Medical University of Lodz, 90-993 Lodz, Poland<i>Background and objectives:</i> A body of evidence confirms the benefits of cardiac rehabilitation (CR) in coronary heart disease (CHD) patients, but it remains unclear whether it enhances the antioxidant potential. The aim of the study was to assess the influence of an eight-week aerobic cycloergometer-based CR program on serum total antioxidant capacity (TAC) and other CHD risk factors. <i>Materials and Methods:</i> The study involved 36 men with CHD (55.2 ± 9.0 years). TAC was assessed with two methods: ferric reducing ability of serum (TAC-FRAS) and 2.2-diphenyl-1-picryl-hydrazyl (TAC-DPPH). Aerobic capacity was evaluated during a submaximal exercise test. TAC and other anthropometric, biochemical and physical activity/fitness measures were performed twice: before the beginning and after termination of CR. <i>Results:</i> Aerobic capacity was higher (7.0 ± 2.6 vs. 8.0 ± 2.5 MET—metabolic equivalents; <i>p</i> < 0.01), but values of resting diastolic blood pressure were lower (81.9 ± 7.6 vs. 77.4 ± 8.9 mmHg; <i>p</i> < 0.01) after termination of CR. Other classic cardiometabolic, anthropometric, and biochemical measures did not change with CR. No difference in TAC-FRAS was found after CR, whereas TAC-DPPH was significantly lower (16.4 ± 4.0 vs. 13.2 ± 3.7% reduction; <i>p</i> < 0.01). <i>Conclusions:</i> Antioxidant potential measured as TAC-DPPH, but not as TAC-FRAS, decreased with the CR program. The recognized health benefits of CR are not related to augmented serum antioxidant status.https://www.mdpi.com/1010-660X/55/4/111exercise trainingphysical performancecardiovascular healthexercise physiologyphysical activityantioxidant potentialuric acid |
| spellingShingle | Anna Gawron-Skarbek Jacek Chrzczanowicz Joanna Kostka Dariusz Nowak Wojciech Drygas Anna Jegier Tomasz Kostka The Influence of an Eight-Week Cycloergometer-Based Cardiac Rehabilitation on Serum Antioxidant Status in Men with Coronary Heart Disease: A Prospective Study Medicina exercise training physical performance cardiovascular health exercise physiology physical activity antioxidant potential uric acid |
| title | The Influence of an Eight-Week Cycloergometer-Based Cardiac Rehabilitation on Serum Antioxidant Status in Men with Coronary Heart Disease: A Prospective Study |
| title_full | The Influence of an Eight-Week Cycloergometer-Based Cardiac Rehabilitation on Serum Antioxidant Status in Men with Coronary Heart Disease: A Prospective Study |
| title_fullStr | The Influence of an Eight-Week Cycloergometer-Based Cardiac Rehabilitation on Serum Antioxidant Status in Men with Coronary Heart Disease: A Prospective Study |
| title_full_unstemmed | The Influence of an Eight-Week Cycloergometer-Based Cardiac Rehabilitation on Serum Antioxidant Status in Men with Coronary Heart Disease: A Prospective Study |
| title_short | The Influence of an Eight-Week Cycloergometer-Based Cardiac Rehabilitation on Serum Antioxidant Status in Men with Coronary Heart Disease: A Prospective Study |
| title_sort | influence of an eight week cycloergometer based cardiac rehabilitation on serum antioxidant status in men with coronary heart disease a prospective study |
| topic | exercise training physical performance cardiovascular health exercise physiology physical activity antioxidant potential uric acid |
| url | https://www.mdpi.com/1010-660X/55/4/111 |
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