Comment on Ceruti et al. Temporal Changes in the Oxyhemoglobin Dissociation Curve of Critically Ill COVID-19 Patients. <i>J. Clin. Med.</i> 2022, <i>11</i>, 788

Ceruti et al. describe in their article very low standard half saturation pressures (P<sub>50</sub>) in COVID-19 patients, calculated with the Dash et al. equations. By using the Hill equation and Severinghaus‘ coefficients we obtained normal values. The authors who do not present a path...

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Bibliographic Details
Main Authors: Dieter Böning, Wilhelm Bloch, Wolfgang M. Kuebler
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/11/12/3376
Description
Summary:Ceruti et al. describe in their article very low standard half saturation pressures (P<sub>50</sub>) in COVID-19 patients, calculated with the Dash et al. equations. By using the Hill equation and Severinghaus‘ coefficients we obtained normal values. The authors who do not present a pathophysiological cause for their results should explain this discrepancy. Independent of the absolute values a continuous moderate decrease of P<sub>50</sub> in the surviving patients might be of clinical importance.
ISSN:2077-0383