Testicular morphology of male rats exposed to Phaleria macrocarpa (Mahkota dewa) aqueous extract
Objective(s):This study was designed to investigate the effect of Phaleria macrocarpa aqueous extract (PM) on spermatogenesis by observing the histological changes of testes in adult male rats. Materials and Methods: PM was prepared by boiling the dried slices of P. macrocarpa fruits followed by fil...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2014-05-01
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| Series: | Iranian Journal of Basic Medical Sciences |
| Subjects: | |
| Online Access: | http://ijbms.mums.ac.ir/pdf_2791_4dafbb8900ca8e37eb2ec470c4f3ac8b.html |
| _version_ | 1828288166363136000 |
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| author | Saadat Parhizkar Suriani Binti Zulkifli Mohammad Aziz Dollah |
| author_facet | Saadat Parhizkar Suriani Binti Zulkifli Mohammad Aziz Dollah |
| author_sort | Saadat Parhizkar |
| collection | DOAJ |
| description | Objective(s):This study was designed to investigate the effect of Phaleria macrocarpa aqueous extract (PM) on spermatogenesis by observing the histological changes of testes in adult male rats. Materials and Methods: PM was prepared by boiling the dried slices of P. macrocarpa fruits followed by filtering, centrifugation and freeze-drying to obtain the powder form. Eighteen Sprague Dawley adult male rats were divided into three groups (six in each group), designated as treatment (240 mg/kg PM), negative control (distilled water) and positive control (4mg/kg testosterone) and administered via intragastric gavage for seven weeks. In the sixth week of supplementation period, each male rat was introduced to five female rats. Afterward, all rats were sacrificed and the testes were removed for histological studies. Results: PM significantly increased the number of cell and the thickness of seminiferous tubules of male rats (P |
| first_indexed | 2024-04-13T09:59:57Z |
| format | Article |
| id | doaj.art-c2e411b9a03c421eba236aa034dfd381 |
| institution | Directory Open Access Journal |
| issn | 2008-3866 2008-3874 |
| language | English |
| last_indexed | 2024-04-13T09:59:57Z |
| publishDate | 2014-05-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Basic Medical Sciences |
| spelling | doaj.art-c2e411b9a03c421eba236aa034dfd3812022-12-22T02:51:16ZengMashhad University of Medical SciencesIranian Journal of Basic Medical Sciences2008-38662008-38742014-05-011753843902791Testicular morphology of male rats exposed to Phaleria macrocarpa (Mahkota dewa) aqueous extractSaadat Parhizkar0Suriani Binti Zulkifli1Mohammad Aziz Dollah2Medicinal Plants Research Centre, Yasuj University of Medical Sciences, Yasuj, IranBiomedical Department, Faculty of Medicine and Health Sciences, University Putra Malaysia, MalaysiaBiomedical Department, Faculty of Medicine and Health Sciences, University Putra Malaysia, MalaysiaObjective(s):This study was designed to investigate the effect of Phaleria macrocarpa aqueous extract (PM) on spermatogenesis by observing the histological changes of testes in adult male rats. Materials and Methods: PM was prepared by boiling the dried slices of P. macrocarpa fruits followed by filtering, centrifugation and freeze-drying to obtain the powder form. Eighteen Sprague Dawley adult male rats were divided into three groups (six in each group), designated as treatment (240 mg/kg PM), negative control (distilled water) and positive control (4mg/kg testosterone) and administered via intragastric gavage for seven weeks. In the sixth week of supplementation period, each male rat was introduced to five female rats. Afterward, all rats were sacrificed and the testes were removed for histological studies. Results: PM significantly increased the number of cell and the thickness of seminiferous tubules of male rats (Phttp://ijbms.mums.ac.ir/pdf_2791_4dafbb8900ca8e37eb2ec470c4f3ac8b.htmlHerbal MedicineInfertilityPhaleria macrocarpaSeminiferous tubulesSpermatogenesis |
| spellingShingle | Saadat Parhizkar Suriani Binti Zulkifli Mohammad Aziz Dollah Testicular morphology of male rats exposed to Phaleria macrocarpa (Mahkota dewa) aqueous extract Iranian Journal of Basic Medical Sciences Herbal Medicine Infertility Phaleria macrocarpa Seminiferous tubules Spermatogenesis |
| title | Testicular morphology of male rats exposed to Phaleria macrocarpa (Mahkota dewa) aqueous extract |
| title_full | Testicular morphology of male rats exposed to Phaleria macrocarpa (Mahkota dewa) aqueous extract |
| title_fullStr | Testicular morphology of male rats exposed to Phaleria macrocarpa (Mahkota dewa) aqueous extract |
| title_full_unstemmed | Testicular morphology of male rats exposed to Phaleria macrocarpa (Mahkota dewa) aqueous extract |
| title_short | Testicular morphology of male rats exposed to Phaleria macrocarpa (Mahkota dewa) aqueous extract |
| title_sort | testicular morphology of male rats exposed to phaleria macrocarpa mahkota dewa aqueous extract |
| topic | Herbal Medicine Infertility Phaleria macrocarpa Seminiferous tubules Spermatogenesis |
| url | http://ijbms.mums.ac.ir/pdf_2791_4dafbb8900ca8e37eb2ec470c4f3ac8b.html |
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