Prevalence, awareness, treatment and control of dyslipidaemia and their determinants: results from a population-based survey of 60 283 residents in eastern China
Objectives To investigate the prevalence, awareness, treatment and control of dyslipidaemia and its associated factors in eastern China.Design Cross-sectional study.Setting Data were collected from the 2017 Nanjing Chronic Disease and Risk Factor Surveillance.Participants This study included 60 283...
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BMJ Publishing Group
2023-12-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/13/12/e075860.full |
| _version_ | 1797371309808680960 |
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| author | Yijia Chen Nan Zhou Xin Hong Weiwei Wang Jinling Du Yingqian Song |
| author_facet | Yijia Chen Nan Zhou Xin Hong Weiwei Wang Jinling Du Yingqian Song |
| author_sort | Yijia Chen |
| collection | DOAJ |
| description | Objectives To investigate the prevalence, awareness, treatment and control of dyslipidaemia and its associated factors in eastern China.Design Cross-sectional study.Setting Data were collected from the 2017 Nanjing Chronic Disease and Risk Factor Surveillance.Participants This study included 60 283 participants aged ≥18 years.Outcome measures Prevalence of dyslipidaemia was defined as self-reported history of dyslipidaemia and/or the use of lipid-lowering medication, and/or meeting at least one of the following during on-site investigation: total cholesterol ≥6.2 mmol/L, triglyceride ≥2.3 mmol/L, low-density lipoprotein cholesterol ≥4.1 mmol/L and high-density lipoprotein cholesterol <1.0 mmol/L. Dyslipidaemia awareness was defined as the proportion of patients with dyslipidaemia who explicitly indicate their awareness of having a diagnosis of dyslipidaemia. Treatment was based on medication use among individuals with dyslipidaemia. Control was defined as having dyslipidaemia, receiving treatment and achieving serum lipid control to the standard level.Analysis Complex weighting was used to calculate weighted prevalence. A two-level logistic regression model determined the influencing factors for dyslipidaemia prevalence, awareness, treatment and control.Results The crude prevalence rate of dyslipidaemia was 28.4% (17 093 of 60 283). Among 17 093 patients with dyslipidaemia, the crude rates of awareness, treatment and control were 40.0% (n=6830), 27.5% (n=4695) and 21.9% (n=3736), respectively. The corresponding weighted prevalence rates were 29.8%, 41.6%, 28.9% and 22.9%. Older age (OR 2.03, 95% CI 1.82 to 2.23), urban residence (1.24, 1.19 to 1.31), higher education level (1.31, 1.21 to 1.42), current smoking (1.22, 1.15 to 1.29), alcohol consumption (1.20, 1.14 to 1.26), obesity (2.13, 1.99 to 2.29), history of hypertension (1.64, 1.56 to 1.71) and diabetes (1.92, 1.80 to 2.04) were identified as independent risk factors for dyslipidaemia (all p<0.001). Participants who were older, female, living in urban areas, had higher education levels, did not smoke or drink alcohol, had central obesity, had hypertension or had diabetes were more likely to be aware of their dyslipidaemia conditions, receive treatment and achieve serum lipid control to a standard level than their comparators (all p<0.05).Conclusions The prevalence of dyslipidaemia is relatively high in eastern China; however, awareness, treatment and control levels are relatively low. |
| first_indexed | 2024-03-08T18:17:57Z |
| format | Article |
| id | doaj.art-c2e510e05cf44295ab45c4402ec77943 |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-03-08T18:17:57Z |
| publishDate | 2023-12-01 |
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| spelling | doaj.art-c2e510e05cf44295ab45c4402ec779432023-12-31T09:30:08ZengBMJ Publishing GroupBMJ Open2044-60552023-12-01131210.1136/bmjopen-2023-075860Prevalence, awareness, treatment and control of dyslipidaemia and their determinants: results from a population-based survey of 60 283 residents in eastern ChinaYijia Chen0Nan Zhou1Xin Hong2Weiwei Wang3Jinling Du4Yingqian Song52 Department of Non-communicable Chronic Disease Control, Jiangsu Provincial Centre for Disease Control and Prevention, Nanjing, ChinaDepartment of Forensic Pathology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, ChinaNon-communicable Disease Prevention, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, ChinaDepartment of Anesthesiology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Institute of Anesthesia and Respiratory Critical Medicine, Jinan, ChinaDepartment of Chronic and Noncommunicable Disease Prevention, Nanjing Medical University Affiliated Nanjing Center for Disease Control and Prevention, Nanjing, ChinaDepartment of Chronic and Noncommunicable Disease Prevention, Nanjing Medical University Affiliated Nanjing Center for Disease Control and Prevention, Nanjing, ChinaObjectives To investigate the prevalence, awareness, treatment and control of dyslipidaemia and its associated factors in eastern China.Design Cross-sectional study.Setting Data were collected from the 2017 Nanjing Chronic Disease and Risk Factor Surveillance.Participants This study included 60 283 participants aged ≥18 years.Outcome measures Prevalence of dyslipidaemia was defined as self-reported history of dyslipidaemia and/or the use of lipid-lowering medication, and/or meeting at least one of the following during on-site investigation: total cholesterol ≥6.2 mmol/L, triglyceride ≥2.3 mmol/L, low-density lipoprotein cholesterol ≥4.1 mmol/L and high-density lipoprotein cholesterol <1.0 mmol/L. Dyslipidaemia awareness was defined as the proportion of patients with dyslipidaemia who explicitly indicate their awareness of having a diagnosis of dyslipidaemia. Treatment was based on medication use among individuals with dyslipidaemia. Control was defined as having dyslipidaemia, receiving treatment and achieving serum lipid control to the standard level.Analysis Complex weighting was used to calculate weighted prevalence. A two-level logistic regression model determined the influencing factors for dyslipidaemia prevalence, awareness, treatment and control.Results The crude prevalence rate of dyslipidaemia was 28.4% (17 093 of 60 283). Among 17 093 patients with dyslipidaemia, the crude rates of awareness, treatment and control were 40.0% (n=6830), 27.5% (n=4695) and 21.9% (n=3736), respectively. The corresponding weighted prevalence rates were 29.8%, 41.6%, 28.9% and 22.9%. Older age (OR 2.03, 95% CI 1.82 to 2.23), urban residence (1.24, 1.19 to 1.31), higher education level (1.31, 1.21 to 1.42), current smoking (1.22, 1.15 to 1.29), alcohol consumption (1.20, 1.14 to 1.26), obesity (2.13, 1.99 to 2.29), history of hypertension (1.64, 1.56 to 1.71) and diabetes (1.92, 1.80 to 2.04) were identified as independent risk factors for dyslipidaemia (all p<0.001). Participants who were older, female, living in urban areas, had higher education levels, did not smoke or drink alcohol, had central obesity, had hypertension or had diabetes were more likely to be aware of their dyslipidaemia conditions, receive treatment and achieve serum lipid control to a standard level than their comparators (all p<0.05).Conclusions The prevalence of dyslipidaemia is relatively high in eastern China; however, awareness, treatment and control levels are relatively low.https://bmjopen.bmj.com/content/13/12/e075860.full |
| spellingShingle | Yijia Chen Nan Zhou Xin Hong Weiwei Wang Jinling Du Yingqian Song Prevalence, awareness, treatment and control of dyslipidaemia and their determinants: results from a population-based survey of 60 283 residents in eastern China BMJ Open |
| title | Prevalence, awareness, treatment and control of dyslipidaemia and their determinants: results from a population-based survey of 60 283 residents in eastern China |
| title_full | Prevalence, awareness, treatment and control of dyslipidaemia and their determinants: results from a population-based survey of 60 283 residents in eastern China |
| title_fullStr | Prevalence, awareness, treatment and control of dyslipidaemia and their determinants: results from a population-based survey of 60 283 residents in eastern China |
| title_full_unstemmed | Prevalence, awareness, treatment and control of dyslipidaemia and their determinants: results from a population-based survey of 60 283 residents in eastern China |
| title_short | Prevalence, awareness, treatment and control of dyslipidaemia and their determinants: results from a population-based survey of 60 283 residents in eastern China |
| title_sort | prevalence awareness treatment and control of dyslipidaemia and their determinants results from a population based survey of 60 283 residents in eastern china |
| url | https://bmjopen.bmj.com/content/13/12/e075860.full |
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