Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes
Latika Sibal1, Sharad C Agarwal2, Philip D Home21Wolfson Diabetes and Endocrine Clinic, Addenbrooke's Hospital, Cambridge, UK; 2Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UKBackground: Diabetes mellitus is associated with a high risk of cardiovascular dise...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2011-01-01
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| Series: | Diabetes, Metabolic Syndrome and Obesity |
| Online Access: | http://www.dovepress.com/carotid-intima-media-thickness-as-a-surrogate-marker-of-cardiovascular-a6078 |
| _version_ | 1811173823431573504 |
|---|---|
| author | Latika Sibal Sharad C Agarwal Philip D Home |
| author_facet | Latika Sibal Sharad C Agarwal Philip D Home |
| author_sort | Latika Sibal |
| collection | DOAJ |
| description | Latika Sibal1, Sharad C Agarwal2, Philip D Home21Wolfson Diabetes and Endocrine Clinic, Addenbrooke's Hospital, Cambridge, UK; 2Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UKBackground: Diabetes mellitus is associated with a high risk of cardiovascular disease. Carotid intima-media thickness (CIMT) is increasingly used as a surrogate marker for atherosclerosis. Its use relies on its ability to predict future clinical cardiovascular end points.Methods: This review examines the evidence linking CIMT as a surrogate marker of vascular complications in people with type 1 and type 2 diabetes. We have also reviewed the various treatment strategies which have been shown to influence CIMT.Conclusions: CIMT measurement is an effective, noninvasive tool which can assist in identifying people with diabetes who are at higher risk of developing microvascular and macrovascular complications. It may also help to evaluate the effectiveness of various treatment strategies used to treat people with diabetes.Keywords: carotid, intima-media thickness, CIMT, diabetes |
| first_indexed | 2024-04-10T17:53:20Z |
| format | Article |
| id | doaj.art-c2e71cbffcc145139a88fc13579e7393 |
| institution | Directory Open Access Journal |
| issn | 1178-7007 |
| language | English |
| last_indexed | 2024-04-10T17:53:20Z |
| publishDate | 2011-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Diabetes, Metabolic Syndrome and Obesity |
| spelling | doaj.art-c2e71cbffcc145139a88fc13579e73932023-02-02T19:40:39ZengDove Medical PressDiabetes, Metabolic Syndrome and Obesity1178-70072011-01-012011default2334Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetesLatika SibalSharad C AgarwalPhilip D HomeLatika Sibal1, Sharad C Agarwal2, Philip D Home21Wolfson Diabetes and Endocrine Clinic, Addenbrooke's Hospital, Cambridge, UK; 2Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UKBackground: Diabetes mellitus is associated with a high risk of cardiovascular disease. Carotid intima-media thickness (CIMT) is increasingly used as a surrogate marker for atherosclerosis. Its use relies on its ability to predict future clinical cardiovascular end points.Methods: This review examines the evidence linking CIMT as a surrogate marker of vascular complications in people with type 1 and type 2 diabetes. We have also reviewed the various treatment strategies which have been shown to influence CIMT.Conclusions: CIMT measurement is an effective, noninvasive tool which can assist in identifying people with diabetes who are at higher risk of developing microvascular and macrovascular complications. It may also help to evaluate the effectiveness of various treatment strategies used to treat people with diabetes.Keywords: carotid, intima-media thickness, CIMT, diabeteshttp://www.dovepress.com/carotid-intima-media-thickness-as-a-surrogate-marker-of-cardiovascular-a6078 |
| spellingShingle | Latika Sibal Sharad C Agarwal Philip D Home Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes Diabetes, Metabolic Syndrome and Obesity |
| title | Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes |
| title_full | Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes |
| title_fullStr | Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes |
| title_full_unstemmed | Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes |
| title_short | Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes |
| title_sort | carotid intima media thickness as a surrogate marker of cardiovascular disease in diabetes |
| url | http://www.dovepress.com/carotid-intima-media-thickness-as-a-surrogate-marker-of-cardiovascular-a6078 |
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