Effect of diet supplemented with enzymatically treated Artemisia annua L. on intestinal digestive function and immunity in weaned pigs
The present experiment was conducted to evaluate the effect of enzymatically treated Artemisia annua L. (EA) on intestinal digestive function and immune capacity in weaned pigs. Firstly, a total of 300 21-day-old piglets were randomly allotted to five groups, including CON, EA1, EA2, EA3, and EA4 gr...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2020-12-01
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| Series: | Italian Journal of Animal Science |
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| Online Access: | http://dx.doi.org/10.1080/1828051X.2020.1826364 |
| _version_ | 1818657912164188160 |
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| author | Yu Niu Yongwei Zhao Jintian He Yang Yun Yong Shi Lili Zhang Tian Wang |
| author_facet | Yu Niu Yongwei Zhao Jintian He Yang Yun Yong Shi Lili Zhang Tian Wang |
| author_sort | Yu Niu |
| collection | DOAJ |
| description | The present experiment was conducted to evaluate the effect of enzymatically treated Artemisia annua L. (EA) on intestinal digestive function and immune capacity in weaned pigs. Firstly, a total of 300 21-day-old piglets were randomly allotted to five groups, including CON, EA1, EA2, EA3, and EA4 groups (basal diet supplemented with 0, 0.5, 1, 2, 4 g/kg EA, respectively). At 50 days of age, the results showed that pigs in the EA3 group presented significant improvements (p < .05) of growth performance and health status when compared with those of the CON group. According to the results above, we considered 2 g/kg EA as the optimal dose for pig diets. Therefore, we selected 12 pigs from the CON and EA3 groups (n = 6) at 51 days of age for further investigation in vivo. Compared with the CON group, EA3 group significantly increased (p < .05) small intestinal length of pigs, enhanced (p < .05) the activities of amylase, trypsin and Na+-K+-ATPase and the concentrations of glucose transporter in both jejunum and ileum. EA3 group had lower (p < .05) concentrations of interleukin 1β, interleukin 6 and tumour necrosis factor α in the jejunum and higher (p < .05) concentrations of interleukin 10, secretory immunoglobulin A and immunoglobulin G in the ileum of pigs than the CON group. These results demonstrated that EA provided a dietary nutritional means to improve intestinal function of weaned pigs and 2 g/kg was the optimal dose for weaned pigs in the present study. |
| first_indexed | 2024-12-17T03:49:01Z |
| format | Article |
| id | doaj.art-c2f1ab24e99a47f2b43af2baca256505 |
| institution | Directory Open Access Journal |
| issn | 1594-4077 1828-051X |
| language | English |
| last_indexed | 2024-12-17T03:49:01Z |
| publishDate | 2020-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Italian Journal of Animal Science |
| spelling | doaj.art-c2f1ab24e99a47f2b43af2baca2565052022-12-21T22:04:49ZengTaylor & Francis GroupItalian Journal of Animal Science1594-40771828-051X2020-12-011911170117910.1080/1828051X.2020.18263641826364Effect of diet supplemented with enzymatically treated Artemisia annua L. on intestinal digestive function and immunity in weaned pigsYu Niu0Yongwei Zhao1Jintian He2Yang Yun3Yong Shi4Lili Zhang5Tian Wang6College of Animal Science and Technology, Nanjing Agricultural UniversityCollege of Animal Science and Technology, Nanjing Agricultural UniversityCollege of Animal Science and Technology, Nanjing Agricultural UniversityCollege of Animal Science and Technology, Nanjing Agricultural UniversityCollege of Animal Science and Technology, Nanjing Agricultural UniversityCollege of Animal Science and Technology, Nanjing Agricultural UniversityCollege of Animal Science and Technology, Nanjing Agricultural UniversityThe present experiment was conducted to evaluate the effect of enzymatically treated Artemisia annua L. (EA) on intestinal digestive function and immune capacity in weaned pigs. Firstly, a total of 300 21-day-old piglets were randomly allotted to five groups, including CON, EA1, EA2, EA3, and EA4 groups (basal diet supplemented with 0, 0.5, 1, 2, 4 g/kg EA, respectively). At 50 days of age, the results showed that pigs in the EA3 group presented significant improvements (p < .05) of growth performance and health status when compared with those of the CON group. According to the results above, we considered 2 g/kg EA as the optimal dose for pig diets. Therefore, we selected 12 pigs from the CON and EA3 groups (n = 6) at 51 days of age for further investigation in vivo. Compared with the CON group, EA3 group significantly increased (p < .05) small intestinal length of pigs, enhanced (p < .05) the activities of amylase, trypsin and Na+-K+-ATPase and the concentrations of glucose transporter in both jejunum and ileum. EA3 group had lower (p < .05) concentrations of interleukin 1β, interleukin 6 and tumour necrosis factor α in the jejunum and higher (p < .05) concentrations of interleukin 10, secretory immunoglobulin A and immunoglobulin G in the ileum of pigs than the CON group. These results demonstrated that EA provided a dietary nutritional means to improve intestinal function of weaned pigs and 2 g/kg was the optimal dose for weaned pigs in the present study.http://dx.doi.org/10.1080/1828051X.2020.1826364enzymatically treated artemisia annua lpigssmall intestinegrowth performancedigestive function |
| spellingShingle | Yu Niu Yongwei Zhao Jintian He Yang Yun Yong Shi Lili Zhang Tian Wang Effect of diet supplemented with enzymatically treated Artemisia annua L. on intestinal digestive function and immunity in weaned pigs Italian Journal of Animal Science enzymatically treated artemisia annua l pigs small intestine growth performance digestive function |
| title | Effect of diet supplemented with enzymatically treated Artemisia annua L. on intestinal digestive function and immunity in weaned pigs |
| title_full | Effect of diet supplemented with enzymatically treated Artemisia annua L. on intestinal digestive function and immunity in weaned pigs |
| title_fullStr | Effect of diet supplemented with enzymatically treated Artemisia annua L. on intestinal digestive function and immunity in weaned pigs |
| title_full_unstemmed | Effect of diet supplemented with enzymatically treated Artemisia annua L. on intestinal digestive function and immunity in weaned pigs |
| title_short | Effect of diet supplemented with enzymatically treated Artemisia annua L. on intestinal digestive function and immunity in weaned pigs |
| title_sort | effect of diet supplemented with enzymatically treated artemisia annua l on intestinal digestive function and immunity in weaned pigs |
| topic | enzymatically treated artemisia annua l pigs small intestine growth performance digestive function |
| url | http://dx.doi.org/10.1080/1828051X.2020.1826364 |
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