Role of estrogen receptor signaling pathway-related genes in diffuse large B-cell lymphoma and identification of key targets via integrated bioinformatics analysis and experimental validation

Role of estrogen receptor signaling pathway-related genes in diffuse large B-cell lymphoma and identification of key targets via integrated bioinformatics analysis and experimental validation

Diffuse large B-cell lymphoma (DLBCL) is a highly heterogeneous malignancy. Epidemiologically, the incidence of DLBCL is higher in men, and the female sex is a favorable prognostic factor, which can be explained by estrogen. This study aimed to explore the potential targets of the estrogen receptor...

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Bibliographic Details
Main Authors: Bo Chen, Tianjiao Mao, Xiuni Qin, Wenqi Zhang, Nobumoto Watanabe, Jiang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Oncology
Subjects:
diffuse large B-cell lymphoma (DLBCL)
estrogen receptor (ER)
biomarker
bioinformatics
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1029998/full

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