Novel Gels: An Emerging Approach for Delivering of Therapeutic Molecules and Recent Trends
Gels are semisolid, homogeneous systems with continuous or discrete therapeutic molecules in a suitable lipophilic or hydrophilic three-dimensional network base. Innovative gel systems possess multipurpose applications in cosmetics, food, pharmaceuticals, biotechnology, and so forth. Formulating a g...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-05-01
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| Series: | Gels |
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| Online Access: | https://www.mdpi.com/2310-2861/8/5/316 |
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| author | Trideva K. Sastri Vishal N. Gupta Souvik Chakraborty Sharadha Madhusudhan Hitesh Kumar Pallavi Chand Vikas Jain Balamuralidhara Veeranna Devegowda V. Gowda |
| author_facet | Trideva K. Sastri Vishal N. Gupta Souvik Chakraborty Sharadha Madhusudhan Hitesh Kumar Pallavi Chand Vikas Jain Balamuralidhara Veeranna Devegowda V. Gowda |
| author_sort | Trideva K. Sastri |
| collection | DOAJ |
| description | Gels are semisolid, homogeneous systems with continuous or discrete therapeutic molecules in a suitable lipophilic or hydrophilic three-dimensional network base. Innovative gel systems possess multipurpose applications in cosmetics, food, pharmaceuticals, biotechnology, and so forth. Formulating a gel-based delivery system is simple and the delivery system enables the release of loaded therapeutic molecules. Furthermore, it facilitates the delivery of molecules via various routes as these gel-based systems offer proximal surface contact between a loaded therapeutic molecule and an absorption site. In the past decade, researchers have potentially explored and established a significant understanding of gel-based delivery systems for drug delivery. Subsequently, they have enabled the prospects of developing novel gel-based systems that illicit drug release by specific biological or external stimuli, such as temperature, pH, enzymes, ultrasound, antigens, etc. These systems are considered smart gels for their broad applications. This review reflects the significant role of advanced gel-based delivery systems for various therapeutic benefits. This detailed discussion is focused on strategies for the formulation of different novel gel-based systems, as well as it highlights the current research trends of these systems and patented technologies. |
| first_indexed | 2024-03-10T03:50:37Z |
| format | Article |
| id | doaj.art-c2f357b59c5c4ce58003aa098eaa8fe9 |
| institution | Directory Open Access Journal |
| issn | 2310-2861 |
| language | English |
| last_indexed | 2024-03-10T03:50:37Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gels |
| spelling | doaj.art-c2f357b59c5c4ce58003aa098eaa8fe92023-11-23T11:08:08ZengMDPI AGGels2310-28612022-05-018531610.3390/gels8050316Novel Gels: An Emerging Approach for Delivering of Therapeutic Molecules and Recent TrendsTrideva K. Sastri0Vishal N. Gupta1Souvik Chakraborty2Sharadha Madhusudhan3Hitesh Kumar4Pallavi Chand5Vikas Jain6Balamuralidhara Veeranna7Devegowda V. Gowda8Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Sri Shivarathreeshwara Nagar, Mysuru 570015, IndiaDepartment of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Sri Shivarathreeshwara Nagar, Mysuru 570015, IndiaDepartment of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Sri Shivarathreeshwara Nagar, Mysuru 570015, IndiaDepartment of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Sri Shivarathreeshwara Nagar, Mysuru 570015, IndiaDepartment of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Sri Shivarathreeshwara Nagar, Mysuru 570015, IndiaDepartment of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Sri Shivarathreeshwara Nagar, Mysuru 570015, IndiaDepartment of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Sri Shivarathreeshwara Nagar, Mysuru 570015, IndiaDepartment of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Sri Shivarathreeshwara Nagar, Mysuru 570015, IndiaDepartment of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Sri Shivarathreeshwara Nagar, Mysuru 570015, IndiaGels are semisolid, homogeneous systems with continuous or discrete therapeutic molecules in a suitable lipophilic or hydrophilic three-dimensional network base. Innovative gel systems possess multipurpose applications in cosmetics, food, pharmaceuticals, biotechnology, and so forth. Formulating a gel-based delivery system is simple and the delivery system enables the release of loaded therapeutic molecules. Furthermore, it facilitates the delivery of molecules via various routes as these gel-based systems offer proximal surface contact between a loaded therapeutic molecule and an absorption site. In the past decade, researchers have potentially explored and established a significant understanding of gel-based delivery systems for drug delivery. Subsequently, they have enabled the prospects of developing novel gel-based systems that illicit drug release by specific biological or external stimuli, such as temperature, pH, enzymes, ultrasound, antigens, etc. These systems are considered smart gels for their broad applications. This review reflects the significant role of advanced gel-based delivery systems for various therapeutic benefits. This detailed discussion is focused on strategies for the formulation of different novel gel-based systems, as well as it highlights the current research trends of these systems and patented technologies.https://www.mdpi.com/2310-2861/8/5/316hydrogelsin situ gelsemulsion gelsmicrogelsnanogelsvesicular gels |
| spellingShingle | Trideva K. Sastri Vishal N. Gupta Souvik Chakraborty Sharadha Madhusudhan Hitesh Kumar Pallavi Chand Vikas Jain Balamuralidhara Veeranna Devegowda V. Gowda Novel Gels: An Emerging Approach for Delivering of Therapeutic Molecules and Recent Trends Gels hydrogels in situ gels emulsion gels microgels nanogels vesicular gels |
| title | Novel Gels: An Emerging Approach for Delivering of Therapeutic Molecules and Recent Trends |
| title_full | Novel Gels: An Emerging Approach for Delivering of Therapeutic Molecules and Recent Trends |
| title_fullStr | Novel Gels: An Emerging Approach for Delivering of Therapeutic Molecules and Recent Trends |
| title_full_unstemmed | Novel Gels: An Emerging Approach for Delivering of Therapeutic Molecules and Recent Trends |
| title_short | Novel Gels: An Emerging Approach for Delivering of Therapeutic Molecules and Recent Trends |
| title_sort | novel gels an emerging approach for delivering of therapeutic molecules and recent trends |
| topic | hydrogels in situ gels emulsion gels microgels nanogels vesicular gels |
| url | https://www.mdpi.com/2310-2861/8/5/316 |
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