Polydatin, A Glycoside of Resveratrol, Is Better Than Resveratrol in Alleviating Non-alcoholic Fatty Liver Disease in Mice Fed a High-Fructose Diet

Polydatin, A Glycoside of Resveratrol, Is Better Than Resveratrol in Alleviating Non-alcoholic Fatty Liver Disease in Mice Fed a High-Fructose Diet

Resveratrol (RES) is considered to be an activator of AMP-activated protein kinase (AMPK) with many reported health benefits. Polydatin (POD) is a natural precursor and glycosylated form of RES. The glycoside structure of POD alters the bioactivity. Overnutrition-stimulated reactive oxygen species (...

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Bibliographic Details
Main Authors: Guangshan Zhao, Lian Yang, Wenshen Zhong, Yuze Hu, Yu Tan, Zhe Ren, Qiuyan Ban, Chung S. Yang, Yifei Wang, Zhiping Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Nutrition
Subjects:
polydatin
resveratrol
non-alcoholic fatty liver disease
5′-aMP-activated protein kinase
gut microbiota
short-chain fatty acids
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.857879/full

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