Pituitary metastatic lesion. Features of diagnosis and surgical interventions
Introduction. Pituitary metastases (PM) are a rare pathology requiring immediate differentiation with other processes of the chiasmosellar region.Objective. To study the features of the clinic and instrumental diagnostics of pituitary metastatic lesion for differential diagnosis with anot...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Romodanov Neurosurgery Institute
2018-03-01
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| Series: | Ukrainian Neurosurgical Journal |
| Online Access: | https://theunj.org/article/view/98083 |
| _version_ | 1797350292847591424 |
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| author | Mykola O. Guk Dmytro S. Teslenko Arthur O. Mumliev Viktor A. Yatsyk Dmytro I. Okonskyi Ruslan V. Aksyonov Dmytro V. Kubryak |
| author_facet | Mykola O. Guk Dmytro S. Teslenko Arthur O. Mumliev Viktor A. Yatsyk Dmytro I. Okonskyi Ruslan V. Aksyonov Dmytro V. Kubryak |
| author_sort | Mykola O. Guk |
| collection | DOAJ |
| description |
Introduction. Pituitary metastases (PM) are a rare pathology requiring immediate differentiation with other processes of the chiasmosellar region.Objective. To study the features of the clinic and instrumental diagnostics of pituitary metastatic lesion for differential diagnosis with another sellar region tumor and determination of indications for surgical treatment.Materials and methods. Seventy-three patients with pituitary metastases were retrospectively analyzed. The patients assessed taking into account the clinical picture, using neuroimaging examinations, hormonal examination.Results. The frequent clinical symptoms in patients with pituitary metastases included diabetes insipidus, oculomotor disorders, visual disturbances and hypopituitarism. The common MRI symptoms for PM were the following: hypophyseal stalk extensive lesions, dumbbell tumor or tumor narrowing in the diaphragmatic aperture, neurohypophysis hypertension loss, increased contrast of the dura mater around the hypophyseal fossa, hypothalamic damage, hyperintensity in the optic tract, intra-tumor hemorrhage. Frequent MSCT- symptom in patients with PM was the destruction of the Turkish saddle walls along with the destruction of adjacent bone formations structure.Conclusions. Based on the analyzed clinical and diagnostic features, indications for surgical intervention were determined and 35 patients with PM were operated. |
| first_indexed | 2024-03-08T12:42:46Z |
| format | Article |
| id | doaj.art-c2fa4473543a49ec922ceb248f2fb71d |
| institution | Directory Open Access Journal |
| issn | 2663-9084 2663-9092 |
| language | English |
| last_indexed | 2024-03-08T12:42:46Z |
| publishDate | 2018-03-01 |
| publisher | Romodanov Neurosurgery Institute |
| record_format | Article |
| series | Ukrainian Neurosurgical Journal |
| spelling | doaj.art-c2fa4473543a49ec922ceb248f2fb71d2024-01-21T08:27:08ZengRomodanov Neurosurgery InstituteUkrainian Neurosurgical Journal2663-90842663-90922018-03-011788310.25305/unj.98083Pituitary metastatic lesion. Features of diagnosis and surgical interventionsMykola O. Guk0https://orcid.org/0000-0003-0614-7364Dmytro S. Teslenko1https://orcid.org/0000-0001-5882-641XArthur O. Mumliev2https://orcid.org/0000-0002-6483-3920Viktor A. Yatsyk3https://orcid.org/0000-0002-7248-2139Dmytro I. Okonskyi4https://orcid.org/0000-0002-7315-1833Ruslan V. Aksyonov5https://orcid.org/0000-0003-3744-6172Dmytro V. Kubryak6https://orcid.org/0000-0002-9439-3030Romodanov Neurosurgery Institute, Kyiv, UkraineRomodanov Neurosurgery Institute, Kyiv, UkraineRomodanov Neurosurgery Institute, Kyiv, UkraineRomodanov Neurosurgery Institute, Kyiv, UkraineRomodanov Neurosurgery Institute, Kyiv, UkraineRomodanov Neurosurgery Institute, Kyiv, UkraineRomodanov Neurosurgery Institute, Kyiv, Ukraine Introduction. Pituitary metastases (PM) are a rare pathology requiring immediate differentiation with other processes of the chiasmosellar region.Objective. To study the features of the clinic and instrumental diagnostics of pituitary metastatic lesion for differential diagnosis with another sellar region tumor and determination of indications for surgical treatment.Materials and methods. Seventy-three patients with pituitary metastases were retrospectively analyzed. The patients assessed taking into account the clinical picture, using neuroimaging examinations, hormonal examination.Results. The frequent clinical symptoms in patients with pituitary metastases included diabetes insipidus, oculomotor disorders, visual disturbances and hypopituitarism. The common MRI symptoms for PM were the following: hypophyseal stalk extensive lesions, dumbbell tumor or tumor narrowing in the diaphragmatic aperture, neurohypophysis hypertension loss, increased contrast of the dura mater around the hypophyseal fossa, hypothalamic damage, hyperintensity in the optic tract, intra-tumor hemorrhage. Frequent MSCT- symptom in patients with PM was the destruction of the Turkish saddle walls along with the destruction of adjacent bone formations structure.Conclusions. Based on the analyzed clinical and diagnostic features, indications for surgical intervention were determined and 35 patients with PM were operated.https://theunj.org/article/view/98083 |
| spellingShingle | Mykola O. Guk Dmytro S. Teslenko Arthur O. Mumliev Viktor A. Yatsyk Dmytro I. Okonskyi Ruslan V. Aksyonov Dmytro V. Kubryak Pituitary metastatic lesion. Features of diagnosis and surgical interventions Ukrainian Neurosurgical Journal |
| title | Pituitary metastatic lesion. Features of diagnosis and surgical interventions |
| title_full | Pituitary metastatic lesion. Features of diagnosis and surgical interventions |
| title_fullStr | Pituitary metastatic lesion. Features of diagnosis and surgical interventions |
| title_full_unstemmed | Pituitary metastatic lesion. Features of diagnosis and surgical interventions |
| title_short | Pituitary metastatic lesion. Features of diagnosis and surgical interventions |
| title_sort | pituitary metastatic lesion features of diagnosis and surgical interventions |
| url | https://theunj.org/article/view/98083 |
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