Exosomal Mir-3613-3p derived from oxygen–glucose deprivation-treated brain microvascular endothelial cell promotes microglial M1 polarization

Exosomal Mir-3613-3p derived from oxygen–glucose deprivation-treated brain microvascular endothelial cell promotes microglial M1 polarization

Abstract Background Brain microvascular endothelial cell (BMEC) injury can affect neuronal survival by modulating immune responses through the microenvironment. Exosomes are important vehicles of transport between cells. However, the regulation of the subtypes of microglia by BMECs through the exoso...

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Bibliographic Details
Main Authors: Mengqi Zhang, Qian Wu, Mimi Tang, Zhuohui Chen, Haiyue Wu
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Cellular & Molecular Biology Letters
Subjects:
Exosome
Ischemic stroke
Brain microvascular endothelial cell
Macrophage
Neuron
Online Access:https://doi.org/10.1186/s11658-023-00432-1

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