Drug Resistance of Acinetobacter in Selected Hospitals
<h2>Background: Nowadays, nosocomial infection with multidrug-resistant Acinetobacter is an important problem in the world, which is facing wide spectrum antibiotics and hence has become resistant.</h2><p><strong>M</strong><strong>aterials and Methods: </strong...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Shahid Beheshti University of Medical Sciences
2015-07-01
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| Series: | Novelty in Biomedicine |
| Subjects: | |
| Online Access: | http://journals.sbmu.ac.ir/index.php/nbm/article/view/7976 |
| _version_ | 1818128836962811904 |
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| author | Davood Yadegarynia Mansoureh Khalili Azad Latif Gachkar Sara Rahmati Roodsari Zahra Arab-Mazar |
| author_facet | Davood Yadegarynia Mansoureh Khalili Azad Latif Gachkar Sara Rahmati Roodsari Zahra Arab-Mazar |
| author_sort | Davood Yadegarynia |
| collection | DOAJ |
| description | <h2>Background: Nowadays, nosocomial infection with multidrug-resistant Acinetobacter is an important problem in the world, which is facing wide spectrum antibiotics and hence has become resistant.</h2><p><strong>M</strong><strong>aterials and Methods: </strong>In this study, positive cultures of Acinetobacter from one hundred clinical samples in seven hospitals from Tehran during 2012-2013 were collected for checking antibiotic susceptibility. Samples test with Ceftazidim, Cefepime, Amikacine and Imipenem by E-test and for Tazocin, Colistin and Tigecycline was performed with disk diffusion method.</p><p><strong>R</strong><strong>es</strong><strong>ults: </strong>For Colistin 10 samples, and for Tazocin, 40 samples were performed by E-test method. Then <em>boumannii</em> species of bacteria and non-<em>baumannii</em> Acinetobacter were separated by PCR and antibiotic susceptibility testing was performed on them. 89% of Acinetobacter samples were <em>boumannii</em> species, which was isolated from respiratory secretions at ICU.</p><p><strong>C</strong><strong>onclusion: </strong>Boumannii and non-boumannii species of bacteria with a high percentage were resistant to Ceftazidim, Amikacine, Cefepime, Tazocin and Imipenem. All baumannii and non-boumannii Acinetobacter were sensitive to Colistin, were only 75% sensitive to Tigecycline, which is a new glycylcycline. Colistin and Tazocin results in samples limited to the E-test method were similar with disk diffusion.</p> |
| first_indexed | 2024-12-11T07:39:35Z |
| format | Article |
| id | doaj.art-c301a5f8598648df87a59fd3a04f8ef2 |
| institution | Directory Open Access Journal |
| issn | 2345-3346 2345-3907 |
| language | English |
| last_indexed | 2024-12-11T07:39:35Z |
| publishDate | 2015-07-01 |
| publisher | Shahid Beheshti University of Medical Sciences |
| record_format | Article |
| series | Novelty in Biomedicine |
| spelling | doaj.art-c301a5f8598648df87a59fd3a04f8ef22022-12-22T01:15:37ZengShahid Beheshti University of Medical SciencesNovelty in Biomedicine2345-33462345-39072015-07-01331031105362Drug Resistance of Acinetobacter in Selected HospitalsDavood Yadegarynia0Mansoureh Khalili Azad1Latif Gachkar2Sara Rahmati Roodsari3Zahra Arab-Mazar4Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR IranInfectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR IranInfectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR IranInfectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR IranInfectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran<h2>Background: Nowadays, nosocomial infection with multidrug-resistant Acinetobacter is an important problem in the world, which is facing wide spectrum antibiotics and hence has become resistant.</h2><p><strong>M</strong><strong>aterials and Methods: </strong>In this study, positive cultures of Acinetobacter from one hundred clinical samples in seven hospitals from Tehran during 2012-2013 were collected for checking antibiotic susceptibility. Samples test with Ceftazidim, Cefepime, Amikacine and Imipenem by E-test and for Tazocin, Colistin and Tigecycline was performed with disk diffusion method.</p><p><strong>R</strong><strong>es</strong><strong>ults: </strong>For Colistin 10 samples, and for Tazocin, 40 samples were performed by E-test method. Then <em>boumannii</em> species of bacteria and non-<em>baumannii</em> Acinetobacter were separated by PCR and antibiotic susceptibility testing was performed on them. 89% of Acinetobacter samples were <em>boumannii</em> species, which was isolated from respiratory secretions at ICU.</p><p><strong>C</strong><strong>onclusion: </strong>Boumannii and non-boumannii species of bacteria with a high percentage were resistant to Ceftazidim, Amikacine, Cefepime, Tazocin and Imipenem. All baumannii and non-boumannii Acinetobacter were sensitive to Colistin, were only 75% sensitive to Tigecycline, which is a new glycylcycline. Colistin and Tazocin results in samples limited to the E-test method were similar with disk diffusion.</p>http://journals.sbmu.ac.ir/index.php/nbm/article/view/7976Acinetobacter, Drug Resistance |
| spellingShingle | Davood Yadegarynia Mansoureh Khalili Azad Latif Gachkar Sara Rahmati Roodsari Zahra Arab-Mazar Drug Resistance of Acinetobacter in Selected Hospitals Novelty in Biomedicine Acinetobacter, Drug Resistance |
| title | Drug Resistance of Acinetobacter in Selected Hospitals |
| title_full | Drug Resistance of Acinetobacter in Selected Hospitals |
| title_fullStr | Drug Resistance of Acinetobacter in Selected Hospitals |
| title_full_unstemmed | Drug Resistance of Acinetobacter in Selected Hospitals |
| title_short | Drug Resistance of Acinetobacter in Selected Hospitals |
| title_sort | drug resistance of acinetobacter in selected hospitals |
| topic | Acinetobacter, Drug Resistance |
| url | http://journals.sbmu.ac.ir/index.php/nbm/article/view/7976 |
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