G2Φnet: Relating genotype and biomechanical phenotype of tissues with deep learning.
Many genetic mutations adversely affect the structure and function of load-bearing soft tissues, with clinical sequelae often responsible for disability or death. Parallel advances in genetics and histomechanical characterization provide significant insight into these conditions, but there remains a...
Main Authors: | Enrui Zhang, Bart Spronck, Jay D Humphrey, George Em Karniadakis |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-10-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1010660 |
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