The Application of Nanobody in CAR-T Therapy

The Application of Nanobody in CAR-T Therapy

Chimeric antigen receptor (CAR) T therapy represents a form of immune cellular therapy with clinical efficacy and a specific target. A typical chimeric antigen receptor (CAR) construct consists of an antigen binding domain, a transmembrane domain, and a cytoplasmic domain. Nanobodies have been widel...

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Bibliographic Details
Main Authors: Chaolemeng Bao, Quanli Gao, Lin-Lin Li, Lu Han, Bingxiang Zhang, Yijin Ding, Zongpei Song, Ruining Zhang, Jishuai Zhang, Xian-Hui Wu
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biomolecules
Subjects:
nanobody
V<sub>H</sub>H
CAR-T
BCMA
Online Access:https://www.mdpi.com/2218-273X/11/2/238

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