Tubo-ovarian mass with raised CA-125 in a 21-year-old female
Abstract Introduction Peritonitis associated with fungal species Curvularia lunata seldom occurs with only five cases reported in the literature, all in middle-age patients with comorbidities undergoing dialysis. Case report A 21-year-old female who was referred to surgical oncology OPD with a diagn...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-06-01
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| Series: | World Journal of Surgical Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12957-022-02651-w |
| _version_ | 1811247852708429824 |
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| author | Roli Purwar Kishan Soni Ragini Tilak Ashish Verma Manoj Pandey |
| author_facet | Roli Purwar Kishan Soni Ragini Tilak Ashish Verma Manoj Pandey |
| author_sort | Roli Purwar |
| collection | DOAJ |
| description | Abstract Introduction Peritonitis associated with fungal species Curvularia lunata seldom occurs with only five cases reported in the literature, all in middle-age patients with comorbidities undergoing dialysis. Case report A 21-year-old female who was referred to surgical oncology OPD with a diagnosis of ovarian malignancy, based on raised cancer antigen 125 (CA 125) and suspected tubo-ovarian mass (TOM) on magnetic resonance imaging (MRI). A review of the MRI showed a pelvic collection with TOM, suggestive of infective pathology. Fungal culture and mass spectroscopy of the cystic collection identified the presence of Curvularia lunata. She was treated with oral itraconazole which showed symptomatic improvement and radiological response. In the follow-up period, the patient developed chest wall swelling, aspiration and geneXpert® revealed multidrug-resistant (MDR) tuberculosis, and treatment was started. Conclusions Unusual causes of TOM and raised CA 125 should be kept in mind when dealing with young patients, as the possibility of epithelial ovarian cancer in this age is very low. |
| first_indexed | 2024-04-12T15:16:44Z |
| format | Article |
| id | doaj.art-c303620b71fa4954ba14135a009e03fd |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-04-12T15:16:44Z |
| publishDate | 2022-06-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-c303620b71fa4954ba14135a009e03fd2022-12-22T03:27:35ZengBMCWorld Journal of Surgical Oncology1477-78192022-06-012011610.1186/s12957-022-02651-wTubo-ovarian mass with raised CA-125 in a 21-year-old femaleRoli Purwar0Kishan Soni1Ragini Tilak2Ashish Verma3Manoj Pandey4Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu UniversityDepartment of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu UniversityDepartment of Microbiology, Institute of Medical Sciences, Banaras Hindu UniversityDepartment of Radiodiagnosis and Imaging, Institute of Medical Sciences, Banaras Hindu UniversityDepartment of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu UniversityAbstract Introduction Peritonitis associated with fungal species Curvularia lunata seldom occurs with only five cases reported in the literature, all in middle-age patients with comorbidities undergoing dialysis. Case report A 21-year-old female who was referred to surgical oncology OPD with a diagnosis of ovarian malignancy, based on raised cancer antigen 125 (CA 125) and suspected tubo-ovarian mass (TOM) on magnetic resonance imaging (MRI). A review of the MRI showed a pelvic collection with TOM, suggestive of infective pathology. Fungal culture and mass spectroscopy of the cystic collection identified the presence of Curvularia lunata. She was treated with oral itraconazole which showed symptomatic improvement and radiological response. In the follow-up period, the patient developed chest wall swelling, aspiration and geneXpert® revealed multidrug-resistant (MDR) tuberculosis, and treatment was started. Conclusions Unusual causes of TOM and raised CA 125 should be kept in mind when dealing with young patients, as the possibility of epithelial ovarian cancer in this age is very low.https://doi.org/10.1186/s12957-022-02651-wPeritonitisInfectionFungalCurvulariaYoung |
| spellingShingle | Roli Purwar Kishan Soni Ragini Tilak Ashish Verma Manoj Pandey Tubo-ovarian mass with raised CA-125 in a 21-year-old female World Journal of Surgical Oncology Peritonitis Infection Fungal Curvularia Young |
| title | Tubo-ovarian mass with raised CA-125 in a 21-year-old female |
| title_full | Tubo-ovarian mass with raised CA-125 in a 21-year-old female |
| title_fullStr | Tubo-ovarian mass with raised CA-125 in a 21-year-old female |
| title_full_unstemmed | Tubo-ovarian mass with raised CA-125 in a 21-year-old female |
| title_short | Tubo-ovarian mass with raised CA-125 in a 21-year-old female |
| title_sort | tubo ovarian mass with raised ca 125 in a 21 year old female |
| topic | Peritonitis Infection Fungal Curvularia Young |
| url | https://doi.org/10.1186/s12957-022-02651-w |
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