Multivariate analysis using high definition flow cytometry reveals distinct T cell repertoires between the foetal-maternal interface and the peripheral blood

Multivariate analysis using high definition flow cytometry reveals distinct T cell repertoires between the foetal-maternal interface and the peripheral blood

The human T-cell compartment is a complex system and while some information is known on repertoire composition and dynamics in the peripheral blood, little is known on repertoire composition at different anatomical sites. Here, we determine the T-cell receptor β-variable (TRBV) repertoire at the dec...

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Bibliographic Details
Main Authors: Michelle eNeller, Brigittie eSantner-Nanan, Rebekah eBrennan, Peter eHsu, Steven eJoung, Ralph eNanan, Scott eBurrows, John J Miles
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Immunology
Subjects:
Placenta
CD4+ T cells
CD8+ T cells
T cell receptor (TCR)
Treg cells
Peripheral Blood
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00033/full

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