Prevalence of soil-transmitted helminths infections among preschool and school-age children in Ethiopia: a systematic review and meta-analysis
Abstract Background There is a lack of comprehensive national data on prevalence, geographical distribution of different species, and temporal trends in soil-helminthiasis (STHs). Therefore, this study aimed to provide a summary and location of the available data on STHs infection among preschool an...
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BMC
2022-03-01
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| Series: | Global Health Research and Policy |
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| Online Access: | https://doi.org/10.1186/s41256-022-00239-1 |
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| author | Legese Chelkeba Zeleke Mekonnen Daniel Emana Worku Jimma Tsegaye Melaku |
| author_facet | Legese Chelkeba Zeleke Mekonnen Daniel Emana Worku Jimma Tsegaye Melaku |
| author_sort | Legese Chelkeba |
| collection | DOAJ |
| description | Abstract Background There is a lack of comprehensive national data on prevalence, geographical distribution of different species, and temporal trends in soil-helminthiasis (STHs). Therefore, this study aimed to provide a summary and location of the available data on STHs infection among preschool and school-age children in Ethiopia. Methods The search was carried out in Medline via PubMed, Scopus, Science Direct, Web of Science, and Google Scholar on data published between 1997 to February 2020 for studies describing the rate of STHs infection among preschool and school-age in Ethiopian. We followed the Patient, Intervention, Comparison, and Outcome (PICO) approach to identify the studies. Meta-regression was performed to understand the trends and to summarize the prevalence using the “metaprop” command using STATA software version 14.0 Results A total of 29,311 of the 61,690 children examined during the period under review were infected with one or more species of intestinal parasites yielding an overall prevalence of 48% (95% CI: 43–53%). The overall pooled estimate of STHs was 33% (95% CI: 28–38%). The prevalence was 44% (95% CI: 31–58%) in SNNPR, 34% (95% CI: 28–41%) in Amhara region, 31% (95% CI: 19–43%) in Oromia region and 10% (95% CI: 7–12%) in Tigray region. Soil-transmitted helminths infection rate has been decreasing from 44% (95% CI: 30–57%) pre-Mass Drug Administration (MDA) era (1997–2012) to 30% (95% CI: 25–34%) post-MDA (2013–2020), although statistically not significant (p = 0.45). A lumbricoides was the predominant species with a prevalence of 17%. Conclusion Southern Nations Nationalities and Peoples Region, Amhara, and Oromia regions carry the highest-burden and are categorized to Moderate Risk Zones (MRZ) and therefore, requiring MDA once annually with Albendazole or Mebendazole. The prevalence of STHs decreased after MDA compared to before MDA, but the decline was not statistically significant. A. lumbricoides was the predominant species of STHs among preschool and school-age children in Ethiopia. The high prevalence of STHs observed in this review, underscores the need for better control and prevention strategies in Ethiopia. |
| first_indexed | 2024-12-13T20:03:25Z |
| format | Article |
| id | doaj.art-c305a0cfcd08462291266995e0555fa5 |
| institution | Directory Open Access Journal |
| issn | 2397-0642 |
| language | English |
| last_indexed | 2024-12-13T20:03:25Z |
| publishDate | 2022-03-01 |
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| series | Global Health Research and Policy |
| spelling | doaj.art-c305a0cfcd08462291266995e0555fa52022-12-21T23:33:07ZengBMCGlobal Health Research and Policy2397-06422022-03-017112310.1186/s41256-022-00239-1Prevalence of soil-transmitted helminths infections among preschool and school-age children in Ethiopia: a systematic review and meta-analysisLegese Chelkeba0Zeleke Mekonnen1Daniel Emana2Worku Jimma3Tsegaye Melaku4Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College Health Sciences, Black Lion Specialized Hospital, Addis Ababa UniversityDepartment of Parasitology, School of Medical Laboratory Sciences, Institute of Health, Jimma UniversityDepartment of Parasitology, School of Medical Laboratory Sciences, Institute of Health, Jimma UniversityDepartment of Information Science, College of Natural Sciences, Jimma UniversityDepartment of Clinical Pharmacy, School of Pharmacy, Institute of Health, Jimma UniversityAbstract Background There is a lack of comprehensive national data on prevalence, geographical distribution of different species, and temporal trends in soil-helminthiasis (STHs). Therefore, this study aimed to provide a summary and location of the available data on STHs infection among preschool and school-age children in Ethiopia. Methods The search was carried out in Medline via PubMed, Scopus, Science Direct, Web of Science, and Google Scholar on data published between 1997 to February 2020 for studies describing the rate of STHs infection among preschool and school-age in Ethiopian. We followed the Patient, Intervention, Comparison, and Outcome (PICO) approach to identify the studies. Meta-regression was performed to understand the trends and to summarize the prevalence using the “metaprop” command using STATA software version 14.0 Results A total of 29,311 of the 61,690 children examined during the period under review were infected with one or more species of intestinal parasites yielding an overall prevalence of 48% (95% CI: 43–53%). The overall pooled estimate of STHs was 33% (95% CI: 28–38%). The prevalence was 44% (95% CI: 31–58%) in SNNPR, 34% (95% CI: 28–41%) in Amhara region, 31% (95% CI: 19–43%) in Oromia region and 10% (95% CI: 7–12%) in Tigray region. Soil-transmitted helminths infection rate has been decreasing from 44% (95% CI: 30–57%) pre-Mass Drug Administration (MDA) era (1997–2012) to 30% (95% CI: 25–34%) post-MDA (2013–2020), although statistically not significant (p = 0.45). A lumbricoides was the predominant species with a prevalence of 17%. Conclusion Southern Nations Nationalities and Peoples Region, Amhara, and Oromia regions carry the highest-burden and are categorized to Moderate Risk Zones (MRZ) and therefore, requiring MDA once annually with Albendazole or Mebendazole. The prevalence of STHs decreased after MDA compared to before MDA, but the decline was not statistically significant. A. lumbricoides was the predominant species of STHs among preschool and school-age children in Ethiopia. The high prevalence of STHs observed in this review, underscores the need for better control and prevention strategies in Ethiopia.https://doi.org/10.1186/s41256-022-00239-1Soil-transmitted helminthsPreschool-age childrenSchool-age childrenMeta-analysisEthiopia |
| spellingShingle | Legese Chelkeba Zeleke Mekonnen Daniel Emana Worku Jimma Tsegaye Melaku Prevalence of soil-transmitted helminths infections among preschool and school-age children in Ethiopia: a systematic review and meta-analysis Global Health Research and Policy Soil-transmitted helminths Preschool-age children School-age children Meta-analysis Ethiopia |
| title | Prevalence of soil-transmitted helminths infections among preschool and school-age children in Ethiopia: a systematic review and meta-analysis |
| title_full | Prevalence of soil-transmitted helminths infections among preschool and school-age children in Ethiopia: a systematic review and meta-analysis |
| title_fullStr | Prevalence of soil-transmitted helminths infections among preschool and school-age children in Ethiopia: a systematic review and meta-analysis |
| title_full_unstemmed | Prevalence of soil-transmitted helminths infections among preschool and school-age children in Ethiopia: a systematic review and meta-analysis |
| title_short | Prevalence of soil-transmitted helminths infections among preschool and school-age children in Ethiopia: a systematic review and meta-analysis |
| title_sort | prevalence of soil transmitted helminths infections among preschool and school age children in ethiopia a systematic review and meta analysis |
| topic | Soil-transmitted helminths Preschool-age children School-age children Meta-analysis Ethiopia |
| url | https://doi.org/10.1186/s41256-022-00239-1 |
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