Genome-wide analysis of unrecognised ethnic group Chuanqing people revealing a close affinity with Southern Han Chinese
Background Chuanqing is an unrecognised ethnic group in Guizhou, southwest China. The genetic history of the Chuanqing people is hotly debated due to a lack of available genetic data. Aim To infer the genetic structure and population history of the Chuanqing people and genetic relationships of the C...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2020-07-01
|
| Series: | Annals of Human Biology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/03014460.2020.1782470 |
| _version_ | 1797685593043369984 |
|---|---|
| author | Jiani Lu Hongling Zhang Zheng Ren Qiyan Wang Yubo Liu Yingxiang Li Guanglin He Jianxin Guo Jing Zhao Rong Hu Lan-Hai Wei Gang Chen Jiang Huang Chuan‑Chao Wang |
| author_facet | Jiani Lu Hongling Zhang Zheng Ren Qiyan Wang Yubo Liu Yingxiang Li Guanglin He Jianxin Guo Jing Zhao Rong Hu Lan-Hai Wei Gang Chen Jiang Huang Chuan‑Chao Wang |
| author_sort | Jiani Lu |
| collection | DOAJ |
| description | Background Chuanqing is an unrecognised ethnic group in Guizhou, southwest China. The genetic history of the Chuanqing people is hotly debated due to a lack of available genetic data. Aim To infer the genetic structure and population history of the Chuanqing people and genetic relationships of the Chuanqing with other East Asians. Subjects and methods We collected samples from 14 Chuanqing individuals from Guizhou and genotyped about 690,000 genome-wide single nucleotide polymorphisms (SNPs). We used Principal Component Analysis (PCA), ADMIXTURE analysis, and f statistics to infer the population genetic structure and admixture. Results Chuanqing people show a distinct genetic profile from indigenous Tai-Kadai and Tibeto-Burman speaking populations in southwest China, but they are genetically similar to southern Han Chinese, Miao, She and Tujia populations. The Han Chinese characteristic Y chromosomal lineages reach high frequencies in the Chuanqing. Conclusions The genetic formation of the Chuanqing people has been greatly influenced by Han Chinese related populations. |
| first_indexed | 2024-03-12T00:46:24Z |
| format | Article |
| id | doaj.art-c306f064852f492e98aaf6b16834eeba |
| institution | Directory Open Access Journal |
| issn | 0301-4460 1464-5033 |
| language | English |
| last_indexed | 2024-03-12T00:46:24Z |
| publishDate | 2020-07-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Human Biology |
| spelling | doaj.art-c306f064852f492e98aaf6b16834eeba2023-09-14T15:36:12ZengTaylor & Francis GroupAnnals of Human Biology0301-44601464-50332020-07-0147546547110.1080/03014460.2020.17824701782470Genome-wide analysis of unrecognised ethnic group Chuanqing people revealing a close affinity with Southern Han ChineseJiani Lu0Hongling Zhang1Zheng Ren2Qiyan Wang3Yubo Liu4Yingxiang Li5Guanglin He6Jianxin Guo7Jing Zhao8Rong Hu9Lan-Hai Wei10Gang Chen11Jiang Huang12Chuan‑Chao Wang13Department of Anthropology and Ethnology, Institute of Anthropology, School of Sociology and Anthropology, and National Institute for Data Science in Health and Medicine, School of Life Sciences, Xiamen UniversityDepartment of Forensic Medicine, Guizhou Medical UniversityDepartment of Forensic Medicine, Guizhou Medical UniversityDepartment of Forensic Medicine, Guizhou Medical UniversityDepartment of Forensic Medicine, Guizhou Medical UniversityDepartment of Anthropology and Ethnology, Institute of Anthropology, School of Sociology and Anthropology, and National Institute for Data Science in Health and Medicine, School of Life Sciences, Xiamen UniversityDepartment of Anthropology and Ethnology, Institute of Anthropology, School of Sociology and Anthropology, and National Institute for Data Science in Health and Medicine, School of Life Sciences, Xiamen UniversityDepartment of Anthropology and Ethnology, Institute of Anthropology, School of Sociology and Anthropology, and National Institute for Data Science in Health and Medicine, School of Life Sciences, Xiamen UniversityDepartment of Anthropology and Ethnology, Institute of Anthropology, School of Sociology and Anthropology, and National Institute for Data Science in Health and Medicine, School of Life Sciences, Xiamen UniversityDepartment of Anthropology and Ethnology, Institute of Anthropology, School of Sociology and Anthropology, and National Institute for Data Science in Health and Medicine, School of Life Sciences, Xiamen UniversityDepartment of Anthropology and Ethnology, Institute of Anthropology, School of Sociology and Anthropology, and National Institute for Data Science in Health and Medicine, School of Life Sciences, Xiamen UniversityWeGeneDepartment of Forensic Medicine, Guizhou Medical UniversityDepartment of Anthropology and Ethnology, Institute of Anthropology, School of Sociology and Anthropology, and National Institute for Data Science in Health and Medicine, School of Life Sciences, Xiamen UniversityBackground Chuanqing is an unrecognised ethnic group in Guizhou, southwest China. The genetic history of the Chuanqing people is hotly debated due to a lack of available genetic data. Aim To infer the genetic structure and population history of the Chuanqing people and genetic relationships of the Chuanqing with other East Asians. Subjects and methods We collected samples from 14 Chuanqing individuals from Guizhou and genotyped about 690,000 genome-wide single nucleotide polymorphisms (SNPs). We used Principal Component Analysis (PCA), ADMIXTURE analysis, and f statistics to infer the population genetic structure and admixture. Results Chuanqing people show a distinct genetic profile from indigenous Tai-Kadai and Tibeto-Burman speaking populations in southwest China, but they are genetically similar to southern Han Chinese, Miao, She and Tujia populations. The Han Chinese characteristic Y chromosomal lineages reach high frequencies in the Chuanqing. Conclusions The genetic formation of the Chuanqing people has been greatly influenced by Han Chinese related populations.http://dx.doi.org/10.1080/03014460.2020.1782470chuanqinggenome-wide genotypingpopulation geneticspopulation admixture |
| spellingShingle | Jiani Lu Hongling Zhang Zheng Ren Qiyan Wang Yubo Liu Yingxiang Li Guanglin He Jianxin Guo Jing Zhao Rong Hu Lan-Hai Wei Gang Chen Jiang Huang Chuan‑Chao Wang Genome-wide analysis of unrecognised ethnic group Chuanqing people revealing a close affinity with Southern Han Chinese Annals of Human Biology chuanqing genome-wide genotyping population genetics population admixture |
| title | Genome-wide analysis of unrecognised ethnic group Chuanqing people revealing a close affinity with Southern Han Chinese |
| title_full | Genome-wide analysis of unrecognised ethnic group Chuanqing people revealing a close affinity with Southern Han Chinese |
| title_fullStr | Genome-wide analysis of unrecognised ethnic group Chuanqing people revealing a close affinity with Southern Han Chinese |
| title_full_unstemmed | Genome-wide analysis of unrecognised ethnic group Chuanqing people revealing a close affinity with Southern Han Chinese |
| title_short | Genome-wide analysis of unrecognised ethnic group Chuanqing people revealing a close affinity with Southern Han Chinese |
| title_sort | genome wide analysis of unrecognised ethnic group chuanqing people revealing a close affinity with southern han chinese |
| topic | chuanqing genome-wide genotyping population genetics population admixture |
| url | http://dx.doi.org/10.1080/03014460.2020.1782470 |
| work_keys_str_mv | AT jianilu genomewideanalysisofunrecognisedethnicgroupchuanqingpeoplerevealingacloseaffinitywithsouthernhanchinese AT honglingzhang genomewideanalysisofunrecognisedethnicgroupchuanqingpeoplerevealingacloseaffinitywithsouthernhanchinese AT zhengren genomewideanalysisofunrecognisedethnicgroupchuanqingpeoplerevealingacloseaffinitywithsouthernhanchinese AT qiyanwang genomewideanalysisofunrecognisedethnicgroupchuanqingpeoplerevealingacloseaffinitywithsouthernhanchinese AT yuboliu genomewideanalysisofunrecognisedethnicgroupchuanqingpeoplerevealingacloseaffinitywithsouthernhanchinese AT yingxiangli genomewideanalysisofunrecognisedethnicgroupchuanqingpeoplerevealingacloseaffinitywithsouthernhanchinese AT guanglinhe genomewideanalysisofunrecognisedethnicgroupchuanqingpeoplerevealingacloseaffinitywithsouthernhanchinese AT jianxinguo genomewideanalysisofunrecognisedethnicgroupchuanqingpeoplerevealingacloseaffinitywithsouthernhanchinese AT jingzhao genomewideanalysisofunrecognisedethnicgroupchuanqingpeoplerevealingacloseaffinitywithsouthernhanchinese AT ronghu genomewideanalysisofunrecognisedethnicgroupchuanqingpeoplerevealingacloseaffinitywithsouthernhanchinese AT lanhaiwei genomewideanalysisofunrecognisedethnicgroupchuanqingpeoplerevealingacloseaffinitywithsouthernhanchinese AT gangchen genomewideanalysisofunrecognisedethnicgroupchuanqingpeoplerevealingacloseaffinitywithsouthernhanchinese AT jianghuang genomewideanalysisofunrecognisedethnicgroupchuanqingpeoplerevealingacloseaffinitywithsouthernhanchinese AT chuanchaowang genomewideanalysisofunrecognisedethnicgroupchuanqingpeoplerevealingacloseaffinitywithsouthernhanchinese |