Ochratoxin A-enhanced glycolysis induces inflammatory responses in human gastric epithelium cells through mTOR/HIF-1α signaling pathway

Ochratoxin A-enhanced glycolysis induces inflammatory responses in human gastric epithelium cells through mTOR/HIF-1α signaling pathway

Ochratoxin A (OTA) is a mycotoxin commonly found in several food commodities worldwide with potential nephrotoxic, hepatotoxic and carcinogenic effects. We previously showed for the first time that OTA treatment enhanced glycolysis in human gastric epithelium (GES-1) cells in vitro. Here, we found t...

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Bibliographic Details
Main Authors: Yuan Wang, Man Zhao, Jinfeng Cui, Hongguang Lian, Zengfang Hao, Lei Lou, Xin Jia, Wei Zhao, Haitao Shen, Lingxiao Xing, Xianghong Zhang
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Ochratoxin A
Gastric epithelium cell
Inflammatory responses
Glycolysis
HIF-1α
MTOR
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323013726

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