Resveratrol attenuates oxidative injury in human umbilical vein endothelial cells through regulating mitochondrial fusion via TyrRS-PARP1 pathway

Resveratrol attenuates oxidative injury in human umbilical vein endothelial cells through regulating mitochondrial fusion via TyrRS-PARP1 pathway

Abstract Background/aims Oxidative stress-induced damage in endothelial cells is a crucial initiator of atherosclerosis (AS), which is highly related to excessive reactive oxygen species (ROS) and mitochondrial dynamics. Resveratrol (RSV) exerts beneficial effects against endothelial oxidative injur...

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Bibliographic Details
Main Authors: Jining Yang, Xi Zhou, Xianglong Zeng, Ou Hu, Long Yi, Mantian Mi
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Nutrition & Metabolism
Subjects:
Endothelial cells
Atherosclerosis
Resveratrol
Mitochondrial dynamics
TyrRS
PARP1
Online Access:http://link.springer.com/article/10.1186/s12986-019-0338-7

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