Mechanistic role of alpha oscillations in a computational model of working memory.
Brain oscillations are believed to be involved in the different operations necessary to manipulate information during working memory tasks. We propose a mechanistic role for the observed inhibition effect of the alpha rhythm based on its interference with the theta rhythm. Using the Lisman-Idiart mo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2024-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0296217&type=printable |
| _version_ | 1797304782859272192 |
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| author | Gustavo Soroka Marco Idiart Aline Villavicencio |
| author_facet | Gustavo Soroka Marco Idiart Aline Villavicencio |
| author_sort | Gustavo Soroka |
| collection | DOAJ |
| description | Brain oscillations are believed to be involved in the different operations necessary to manipulate information during working memory tasks. We propose a mechanistic role for the observed inhibition effect of the alpha rhythm based on its interference with the theta rhythm. Using the Lisman-Idiart model for multi-item working memory, we show that the interaction between these two oscillations is capable of creating a long lasting destructive interference that prevents the cyclic reactivation of neuronal ensembles and, as a consequence, memory maintenance. Additionally, to ensure robustness we propose a modular version of the model and implement oscillations as traveling waves. Using this model, we show that the interactions between theta and gamma determine the allocation of multiple memories in distinct modules, while the interference between theta and alpha disrupts the maintenance of the information already stored in them. The effect of alpha in erasing or blocking storage is robust and seems fairly independent of frequency, as long as it stays within the alpha range. This model helps us to understand why the alpha and theta oscillations, which have close frequency bands, could have opposite roles in working memory. |
| first_indexed | 2024-03-08T00:15:28Z |
| format | Article |
| id | doaj.art-c30fcd40024243118c970fe9ae988756 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-03-08T00:15:28Z |
| publishDate | 2024-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-c30fcd40024243118c970fe9ae9887562024-02-17T05:33:08ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-01192e029621710.1371/journal.pone.0296217Mechanistic role of alpha oscillations in a computational model of working memory.Gustavo SorokaMarco IdiartAline VillavicencioBrain oscillations are believed to be involved in the different operations necessary to manipulate information during working memory tasks. We propose a mechanistic role for the observed inhibition effect of the alpha rhythm based on its interference with the theta rhythm. Using the Lisman-Idiart model for multi-item working memory, we show that the interaction between these two oscillations is capable of creating a long lasting destructive interference that prevents the cyclic reactivation of neuronal ensembles and, as a consequence, memory maintenance. Additionally, to ensure robustness we propose a modular version of the model and implement oscillations as traveling waves. Using this model, we show that the interactions between theta and gamma determine the allocation of multiple memories in distinct modules, while the interference between theta and alpha disrupts the maintenance of the information already stored in them. The effect of alpha in erasing or blocking storage is robust and seems fairly independent of frequency, as long as it stays within the alpha range. This model helps us to understand why the alpha and theta oscillations, which have close frequency bands, could have opposite roles in working memory.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0296217&type=printable |
| spellingShingle | Gustavo Soroka Marco Idiart Aline Villavicencio Mechanistic role of alpha oscillations in a computational model of working memory. PLoS ONE |
| title | Mechanistic role of alpha oscillations in a computational model of working memory. |
| title_full | Mechanistic role of alpha oscillations in a computational model of working memory. |
| title_fullStr | Mechanistic role of alpha oscillations in a computational model of working memory. |
| title_full_unstemmed | Mechanistic role of alpha oscillations in a computational model of working memory. |
| title_short | Mechanistic role of alpha oscillations in a computational model of working memory. |
| title_sort | mechanistic role of alpha oscillations in a computational model of working memory |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0296217&type=printable |
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