Tumor-associated macrophages in colorectal cancer metastasis: molecular insights and translational perspectives

Tumor-associated macrophages in colorectal cancer metastasis: molecular insights and translational perspectives

Abstract Metastasis is the leading cause of high mortality in colorectal cancer (CRC), which is not only driven by changes occurring within the tumor cells, but is also influenced by the dynamic interaction between cancer cells and components in the tumor microenvironment (TME). Currently, the explo...

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Bibliographic Details
Main Authors: Siyu Hou, Yuanchun Zhao, Jiajia Chen, Yuxin Lin, Xin Qi
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Translational Medicine
Subjects:
CRC metastasis
Macrophage
TAM
TME
Personalized therapy
Online Access:https://doi.org/10.1186/s12967-024-04856-x

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