Risk of atrial fibrillation in patients with multiple myeloma: what is known and directions for future study
Abstract Background Multiple myeloma (MM) is a prevalent hematological tumor, and recent clinical data have highlighted the significance of atrial fibrillation (AF) as a crucial complication affecting the prognosis of MM. This review aims to consolidate findings from published clinical studies, focu...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2024-02-01
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| Series: | The Egyptian Heart Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43044-023-00434-6 |
| _version_ | 1797274190636646400 |
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| author | Ting Fu Yuxiao Chen Lian Lou Zhihang Li Wen Shi Xuan Zhang Jian Yang |
| author_facet | Ting Fu Yuxiao Chen Lian Lou Zhihang Li Wen Shi Xuan Zhang Jian Yang |
| author_sort | Ting Fu |
| collection | DOAJ |
| description | Abstract Background Multiple myeloma (MM) is a prevalent hematological tumor, and recent clinical data have highlighted the significance of atrial fibrillation (AF) as a crucial complication affecting the prognosis of MM. This review aims to consolidate findings from published clinical studies, focusing on the epidemiological characteristics of AF in MM patients and the associated risks arising from MM treatments such as autologous hematopoietic stem cell transplantation, proteasome inhibitors, and immunomodulatory agents. Main body While existing data partially demonstrate a strong correlation between MM and AF, further clinical studies are necessary to comprehensively investigate their association. These studies should encompass various aspects, including the risk of AF resulting from MM treatment, the impact of AF-induced embolic events and heart failure on MM prognosis, as well as the influence of AF management methods like catheter ablation or left atrial appendage closure on MM prognosis. Conclusions The supplementation of future data will provide more precise guidance for managing MM patients. By incorporating information regarding AF risk associated with MM treatment and examining the effects of AF management strategies on MM prognosis, healthcare professionals can enhance their decision-making process when caring for individuals with MM. |
| first_indexed | 2024-03-07T14:55:48Z |
| format | Article |
| id | doaj.art-c31e1993dd9e4d6a99aafff33df1e5a8 |
| institution | Directory Open Access Journal |
| issn | 2090-911X |
| language | English |
| last_indexed | 2024-03-07T14:55:48Z |
| publishDate | 2024-02-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Heart Journal |
| spelling | doaj.art-c31e1993dd9e4d6a99aafff33df1e5a82024-03-05T19:29:00ZengSpringerOpenThe Egyptian Heart Journal2090-911X2024-02-017611710.1186/s43044-023-00434-6Risk of atrial fibrillation in patients with multiple myeloma: what is known and directions for future studyTing Fu0Yuxiao Chen1Lian Lou2Zhihang Li3Wen Shi4Xuan Zhang5Jian Yang6Department of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang UniversityDepartment of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang UniversityDepartment of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang UniversityDepartment of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang UniversityDepartment of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang UniversityDepartment of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang UniversityDepartment of Cardiology, The First Affiliated Hospital, College of Medicine, Zhejiang UniversityAbstract Background Multiple myeloma (MM) is a prevalent hematological tumor, and recent clinical data have highlighted the significance of atrial fibrillation (AF) as a crucial complication affecting the prognosis of MM. This review aims to consolidate findings from published clinical studies, focusing on the epidemiological characteristics of AF in MM patients and the associated risks arising from MM treatments such as autologous hematopoietic stem cell transplantation, proteasome inhibitors, and immunomodulatory agents. Main body While existing data partially demonstrate a strong correlation between MM and AF, further clinical studies are necessary to comprehensively investigate their association. These studies should encompass various aspects, including the risk of AF resulting from MM treatment, the impact of AF-induced embolic events and heart failure on MM prognosis, as well as the influence of AF management methods like catheter ablation or left atrial appendage closure on MM prognosis. Conclusions The supplementation of future data will provide more precise guidance for managing MM patients. By incorporating information regarding AF risk associated with MM treatment and examining the effects of AF management strategies on MM prognosis, healthcare professionals can enhance their decision-making process when caring for individuals with MM.https://doi.org/10.1186/s43044-023-00434-6Multiple myelomaAtrial fibrillation |
| spellingShingle | Ting Fu Yuxiao Chen Lian Lou Zhihang Li Wen Shi Xuan Zhang Jian Yang Risk of atrial fibrillation in patients with multiple myeloma: what is known and directions for future study The Egyptian Heart Journal Multiple myeloma Atrial fibrillation |
| title | Risk of atrial fibrillation in patients with multiple myeloma: what is known and directions for future study |
| title_full | Risk of atrial fibrillation in patients with multiple myeloma: what is known and directions for future study |
| title_fullStr | Risk of atrial fibrillation in patients with multiple myeloma: what is known and directions for future study |
| title_full_unstemmed | Risk of atrial fibrillation in patients with multiple myeloma: what is known and directions for future study |
| title_short | Risk of atrial fibrillation in patients with multiple myeloma: what is known and directions for future study |
| title_sort | risk of atrial fibrillation in patients with multiple myeloma what is known and directions for future study |
| topic | Multiple myeloma Atrial fibrillation |
| url | https://doi.org/10.1186/s43044-023-00434-6 |
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