Genome-wide DNA methylation differences according to oestrogen receptor beta status in colorectal cancer

Genome-wide DNA methylation differences according to oestrogen receptor beta status in colorectal cancer

Involvement of sex hormones in colorectal cancer (CRC) development has been linked to oestrogen receptor β (ERβ). Expression of ERβ is found reduced in tumour tissue and inversely related to mortality. However, mechanisms are not well understood. Our study aimed to detect differentially methylated g...

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Bibliographic Details
Main Authors: Sonja Neumeyer, Odilia Popanda, Dominic Edelmann, Katja Butterbach, Csaba Toth, Wilfried Roth, Hendrik Bläker, Ruijingfang Jiang, Esther Herpel, Cornelia Jäkel, Peter Schmezer, Lina Jansen, Elizabeth Alwers, Axel Benner, Barbara Burwinkel, Michael Hoffmeister, Hermann Brenner, Jenny Chang-Claude
Format: Article
Language:English
Published: Taylor & Francis Group 2019-05-01
Series:Epigenetics
Subjects:
colon
ewas
differential methylation
erβ
sex hormones
methylation profiling
epigenetics
Online Access:http://dx.doi.org/10.1080/15592294.2019.1595998

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