The Potential of Siglecs and Sialic Acids as Biomarkers and Therapeutic Targets in Tumor Immunotherapy

The Potential of Siglecs and Sialic Acids as Biomarkers and Therapeutic Targets in Tumor Immunotherapy

The dysregulation of sialic acid is closely associated with oncogenesis and tumor progression. Most tumor cells exhibit sialic acid upregulation. Sialic acid-binding immunoglobulin-like lectins (Siglecs) are receptors that recognize sialic acid and are expressed in various immune cells. The activity...

Full description

Bibliographic Details
Main Authors: Haokang Feng, Jiale Feng, Xu Han, Ying Ying, Wenhui Lou, Liang Liu, Lei Zhang
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
Siglecs
immune checkpoint inhibitors
sialylation
immune cells
immune evasion
Online Access:https://www.mdpi.com/2072-6694/16/2/289

Similar Items

Similar Items