Use of Catridecacog in a patient with severe Factor XIII deficiency undergoing surgery
Despite many articles regarding the antihemorrhagic treatment and prophylaxis, there is a lack of experience about how to best conduct major surgical procedures in patients with congenital factor XIII (FXIII) deficiency. Here we report a case of surgery (right inguinal hernia, complicated by heavine...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-02-01
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| Series: | Hematology Reports |
| Subjects: | |
| Online Access: | https://www.pagepress.org/journals/index.php/hr/article/view/7912 |
| _version_ | 1797935640569970688 |
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| author | Gianluca Sottilotta Francesca Luise Vincenzo Oriana Angela Piromalli Rosa Santacroce Alessandra Di Lelio |
| author_facet | Gianluca Sottilotta Francesca Luise Vincenzo Oriana Angela Piromalli Rosa Santacroce Alessandra Di Lelio |
| author_sort | Gianluca Sottilotta |
| collection | DOAJ |
| description | Despite many articles regarding the antihemorrhagic treatment and prophylaxis, there is a lack of experience about how to best conduct major surgical procedures in patients with congenital factor XIII (FXIII) deficiency. Here we report a case of surgery (right inguinal hernia, complicated by heaviness and pain) performed in a patient with FXIII deficiency, receiving recombinant FXIII prophylaxis (Catridecacog 35 UI/kg every 28±2 days). Our experience shows that Catridecacog can be used safely and effectively not only for continued prophylaxis but also in surgery and adds to the very limited body of evidence currently available on surgery in this bleeding disorder. |
| first_indexed | 2024-04-10T18:18:20Z |
| format | Article |
| id | doaj.art-c3214c7de4084157868b569a124706b7 |
| institution | Directory Open Access Journal |
| issn | 2038-8322 2038-8330 |
| language | English |
| last_indexed | 2024-04-10T18:18:20Z |
| publishDate | 2019-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Hematology Reports |
| spelling | doaj.art-c3214c7de4084157868b569a124706b72023-02-02T08:14:45ZengMDPI AGHematology Reports2038-83222038-83302019-02-0111110.4081/hr.2019.7912Use of Catridecacog in a patient with severe Factor XIII deficiency undergoing surgeryGianluca Sottilotta0Francesca Luise1Vincenzo Oriana2Angela Piromalli3Rosa Santacroce4Alessandra Di Lelio5UOSD Microcitemie – Centro Emofilia – Servizio Emostasi e Trombosi, Grande Ospedale Metropolitano Bianchi- Melacrino-Morelli, Reggio CalabriaUOSD Microcitemie - Centro Emofilia – Servizio Emostasi e Trombosi - Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio CalabriaUOSD Microcitemie - Centro Emofilia – Servizio Emostasi e Trombosi - Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio CalabriaUOSD Microcitemie - Centro Emofilia – Servizio Emostasi e Trombosi - Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio CalabriaServizio di Genetica Medica, Azienda Ospedaliero-Universitaria Ospedali Riuniti di FoggiaCenter for Outcomes Research and Clinical Epidemiology – CORESEARCH, PescaraDespite many articles regarding the antihemorrhagic treatment and prophylaxis, there is a lack of experience about how to best conduct major surgical procedures in patients with congenital factor XIII (FXIII) deficiency. Here we report a case of surgery (right inguinal hernia, complicated by heaviness and pain) performed in a patient with FXIII deficiency, receiving recombinant FXIII prophylaxis (Catridecacog 35 UI/kg every 28±2 days). Our experience shows that Catridecacog can be used safely and effectively not only for continued prophylaxis but also in surgery and adds to the very limited body of evidence currently available on surgery in this bleeding disorder.https://www.pagepress.org/journals/index.php/hr/article/view/7912Recombinant FXIIIcongenital FXIII deficiencysurgery |
| spellingShingle | Gianluca Sottilotta Francesca Luise Vincenzo Oriana Angela Piromalli Rosa Santacroce Alessandra Di Lelio Use of Catridecacog in a patient with severe Factor XIII deficiency undergoing surgery Hematology Reports Recombinant FXIII congenital FXIII deficiency surgery |
| title | Use of Catridecacog in a patient with severe Factor XIII deficiency undergoing surgery |
| title_full | Use of Catridecacog in a patient with severe Factor XIII deficiency undergoing surgery |
| title_fullStr | Use of Catridecacog in a patient with severe Factor XIII deficiency undergoing surgery |
| title_full_unstemmed | Use of Catridecacog in a patient with severe Factor XIII deficiency undergoing surgery |
| title_short | Use of Catridecacog in a patient with severe Factor XIII deficiency undergoing surgery |
| title_sort | use of catridecacog in a patient with severe factor xiii deficiency undergoing surgery |
| topic | Recombinant FXIII congenital FXIII deficiency surgery |
| url | https://www.pagepress.org/journals/index.php/hr/article/view/7912 |
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