Diagnostic performance of conventional ultrasound and quantitative and qualitative real-time shear wave elastography in musculoskeletal soft tissue tumors
Abstract Background To explore the feasibility to identify malignant musculoskeletal soft tissue tumors using real-time shear wave elastography (rtSWE). Methods One hundred fifteen musculoskeletal soft tissue tumors in 92 consecutive patients were examined using both conventional ultrasonography (US...
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| Format: | Article |
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BMC
2020-03-01
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| Series: | Journal of Orthopaedic Surgery and Research |
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| Online Access: | http://link.springer.com/article/10.1186/s13018-020-01620-x |
| _version_ | 1818014091359289344 |
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| author | Ao Li Xiao-Jing Peng Qian Ma Ye Dong Cui-Lian Mao Yu Hu |
| author_facet | Ao Li Xiao-Jing Peng Qian Ma Ye Dong Cui-Lian Mao Yu Hu |
| author_sort | Ao Li |
| collection | DOAJ |
| description | Abstract Background To explore the feasibility to identify malignant musculoskeletal soft tissue tumors using real-time shear wave elastography (rtSWE). Methods One hundred fifteen musculoskeletal soft tissue tumors in 92 consecutive patients were examined using both conventional ultrasonography (US) and rtSWE. For each patient, the rtSWE parameters including maximum elasticity (E max), mean elasticity (E mean), minimum elasticity (E min), standard deviation of the elasticity (E sd), and rtSWE image pattern were obtained. Eighty-one histopathologically confirmed tumors from 73 patients were subjected to analysis. Results The 81 lesions included in the study were histopathologically classified as malignant (n = 21) or benign (n = 60). The statistically significant differences between benign and malignant lesions were found in conventional US characters including size, depth, margin, echogenicity, mass texture, and power Doppler signal. Meanwhile, the significant differences were also found in quantitative rtSWE findings including E max, E mean, E min, and E sd values and in qualitative rtSWE parameter named rtSWE image pattern. Multivariate analysis showed that infiltrative margin (OR, 4.470), and size (OR, 1.046) were independent predictors for malignancy in US findings, while E sd value (OR, 9.047) was independent predictors for malignancy in quantitative rtSWE parameters. Areas under the ROC curve (Azs) for US features, Esd value, and rtSWE image pattern were 0.851, 0.795, and 0.792, respectively. Conclusions Conventional US and quantitative and qualitative rtSWE parameters are useful for malignancy prediction of musculoskeletal soft tissue tumors. rtSWE can be used to supplement conventional US to diagnose musculoskeletal soft tissue tumors. |
| first_indexed | 2024-04-14T06:41:24Z |
| format | Article |
| id | doaj.art-c3234b38d0b246d58b498c55ee7bc489 |
| institution | Directory Open Access Journal |
| issn | 1749-799X |
| language | English |
| last_indexed | 2024-04-14T06:41:24Z |
| publishDate | 2020-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj.art-c3234b38d0b246d58b498c55ee7bc4892022-12-22T02:07:20ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2020-03-011511710.1186/s13018-020-01620-xDiagnostic performance of conventional ultrasound and quantitative and qualitative real-time shear wave elastography in musculoskeletal soft tissue tumorsAo Li0Xiao-Jing Peng1Qian Ma2Ye Dong3Cui-Lian Mao4Yu Hu5Department of Ultrasound, the First Affiliated Hospital of Nanjing Medical UniversityDepartment of Ultrasound, the First Affiliated Hospital of Nanjing Medical UniversityDepartment of Ultrasound, the First Affiliated Hospital of Nanjing Medical UniversityDepartment of Ultrasound, the First Affiliated Hospital of Nanjing Medical UniversityDepartment of Ultrasound, the First Affiliated Hospital of Nanjing Medical UniversityDepartment of Ultrasound, the First Affiliated Hospital of Nanjing Medical UniversityAbstract Background To explore the feasibility to identify malignant musculoskeletal soft tissue tumors using real-time shear wave elastography (rtSWE). Methods One hundred fifteen musculoskeletal soft tissue tumors in 92 consecutive patients were examined using both conventional ultrasonography (US) and rtSWE. For each patient, the rtSWE parameters including maximum elasticity (E max), mean elasticity (E mean), minimum elasticity (E min), standard deviation of the elasticity (E sd), and rtSWE image pattern were obtained. Eighty-one histopathologically confirmed tumors from 73 patients were subjected to analysis. Results The 81 lesions included in the study were histopathologically classified as malignant (n = 21) or benign (n = 60). The statistically significant differences between benign and malignant lesions were found in conventional US characters including size, depth, margin, echogenicity, mass texture, and power Doppler signal. Meanwhile, the significant differences were also found in quantitative rtSWE findings including E max, E mean, E min, and E sd values and in qualitative rtSWE parameter named rtSWE image pattern. Multivariate analysis showed that infiltrative margin (OR, 4.470), and size (OR, 1.046) were independent predictors for malignancy in US findings, while E sd value (OR, 9.047) was independent predictors for malignancy in quantitative rtSWE parameters. Areas under the ROC curve (Azs) for US features, Esd value, and rtSWE image pattern were 0.851, 0.795, and 0.792, respectively. Conclusions Conventional US and quantitative and qualitative rtSWE parameters are useful for malignancy prediction of musculoskeletal soft tissue tumors. rtSWE can be used to supplement conventional US to diagnose musculoskeletal soft tissue tumors.http://link.springer.com/article/10.1186/s13018-020-01620-xMusculoskeletal soft tissue tumorUltrasoundReal timeShear wave elastography |
| spellingShingle | Ao Li Xiao-Jing Peng Qian Ma Ye Dong Cui-Lian Mao Yu Hu Diagnostic performance of conventional ultrasound and quantitative and qualitative real-time shear wave elastography in musculoskeletal soft tissue tumors Journal of Orthopaedic Surgery and Research Musculoskeletal soft tissue tumor Ultrasound Real time Shear wave elastography |
| title | Diagnostic performance of conventional ultrasound and quantitative and qualitative real-time shear wave elastography in musculoskeletal soft tissue tumors |
| title_full | Diagnostic performance of conventional ultrasound and quantitative and qualitative real-time shear wave elastography in musculoskeletal soft tissue tumors |
| title_fullStr | Diagnostic performance of conventional ultrasound and quantitative and qualitative real-time shear wave elastography in musculoskeletal soft tissue tumors |
| title_full_unstemmed | Diagnostic performance of conventional ultrasound and quantitative and qualitative real-time shear wave elastography in musculoskeletal soft tissue tumors |
| title_short | Diagnostic performance of conventional ultrasound and quantitative and qualitative real-time shear wave elastography in musculoskeletal soft tissue tumors |
| title_sort | diagnostic performance of conventional ultrasound and quantitative and qualitative real time shear wave elastography in musculoskeletal soft tissue tumors |
| topic | Musculoskeletal soft tissue tumor Ultrasound Real time Shear wave elastography |
| url | http://link.springer.com/article/10.1186/s13018-020-01620-x |
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