RADIORESISTANCE OF THE TUMOR AND ITS SOLUTIONS (LITERATURE REVIEW)

Presented article is a review of domestic and foreign literature on the application of radiomodifying drugs with electron-affinic properties (metronidazole and its derivatives) with the aim of increasing the effectiveness of radiation therapy. The mechanism of action and properties of the electron-a...

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Main Authors: Yu. A. Barsukov, A. G. Malikhov, S. I. Tkachev, D. V. Kuzmichev
Format: Article
Language:Russian
Published: “ABV-press” Publishing house”, LLC 2015-05-01
Series:Тазовая хирургия и онкология
Subjects:
Online Access:https://ok.abvpress.ru/jour/article/view/120
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author Yu. A. Barsukov
A. G. Malikhov
S. I. Tkachev
D. V. Kuzmichev
author_facet Yu. A. Barsukov
A. G. Malikhov
S. I. Tkachev
D. V. Kuzmichev
author_sort Yu. A. Barsukov
collection DOAJ
description Presented article is a review of domestic and foreign literature on the application of radiomodifying drugs with electron-affinic properties (metronidazole and its derivatives) with the aim of increasing the effectiveness of radiation therapy. The mechanism of action and properties of the electron-affinic drugs of is described. Special attention is paid to the creation of a new medicinal form of metronidazole with the hydrogel-based biopolymer and its inclusion in combined treatment of resectable and locally advanced rectal cancer.
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spelling doaj.art-c323d29d475843769a97aa2a4cc20a142023-08-02T07:48:52Zrus“ABV-press” Publishing house”, LLCТазовая хирургия и онкология2686-95942015-05-015191910.17650/2220-3478-2015-1-9-19104RADIORESISTANCE OF THE TUMOR AND ITS SOLUTIONS (LITERATURE REVIEW)Yu. A. Barsukov0A. G. Malikhov1S. I. Tkachev2D. V. Kuzmichev3N.N. Blokhin Russian Cancer Research CenterN.N. Blokhin Russian Cancer Research CenterN.N. Blokhin Russian Cancer Research CenterN.N. Blokhin Russian Cancer Research CenterPresented article is a review of domestic and foreign literature on the application of radiomodifying drugs with electron-affinic properties (metronidazole and its derivatives) with the aim of increasing the effectiveness of radiation therapy. The mechanism of action and properties of the electron-affinic drugs of is described. Special attention is paid to the creation of a new medicinal form of metronidazole with the hydrogel-based biopolymer and its inclusion in combined treatment of resectable and locally advanced rectal cancer.https://ok.abvpress.ru/jour/article/view/120electronacceptor compoundsmetronidazole and its derivatives
spellingShingle Yu. A. Barsukov
A. G. Malikhov
S. I. Tkachev
D. V. Kuzmichev
RADIORESISTANCE OF THE TUMOR AND ITS SOLUTIONS (LITERATURE REVIEW)
Тазовая хирургия и онкология
electronacceptor compounds
metronidazole and its derivatives
title RADIORESISTANCE OF THE TUMOR AND ITS SOLUTIONS (LITERATURE REVIEW)
title_full RADIORESISTANCE OF THE TUMOR AND ITS SOLUTIONS (LITERATURE REVIEW)
title_fullStr RADIORESISTANCE OF THE TUMOR AND ITS SOLUTIONS (LITERATURE REVIEW)
title_full_unstemmed RADIORESISTANCE OF THE TUMOR AND ITS SOLUTIONS (LITERATURE REVIEW)
title_short RADIORESISTANCE OF THE TUMOR AND ITS SOLUTIONS (LITERATURE REVIEW)
title_sort radioresistance of the tumor and its solutions literature review
topic electronacceptor compounds
metronidazole and its derivatives
url https://ok.abvpress.ru/jour/article/view/120
work_keys_str_mv AT yuabarsukov radioresistanceofthetumoranditssolutionsliteraturereview
AT agmalikhov radioresistanceofthetumoranditssolutionsliteraturereview
AT sitkachev radioresistanceofthetumoranditssolutionsliteraturereview
AT dvkuzmichev radioresistanceofthetumoranditssolutionsliteraturereview