Common SPINK-1 mutations do not predispose to the development of non-alcoholic fatty liver disease

Common SPINK-1 mutations do not predispose to the development of non-alcoholic fatty liver disease

Background: Non-alcoholic fatty liver disease (NAFLD) is common in obese and diabetics. Serine protease inhibitor Kazal-1 (SPINK-1) protein is highly expressed in the liver and adipose tissue of diabetic and obese suggesting its role in NAFLD. SPINK-1 also behaves as an acute phase reactant protein....

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Bibliographic Details
Main Authors: Nevin Oruc;, Omer Ozutemiz;, Ulus Salih Akarca;, Afig Berdeli;, Galip Ersoz;, Fulya Gunsar;, Zeki Karasu;, Tankut Ilter;, Yucel Batur
Format: Article
Language:English
Published: Elsevier 2009-04-01
Series:Annals of Hepatology
Subjects:
SPINK1
NAFLD
mutation
insulin resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119317880

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