Carisoprodol withdrawal syndrome resembling neuroleptic malignant syndrome: Diagnostic dilemma
Soma (Carisoprodol) is N-isopropyl-2 methyl-2-propyl-1,3-propanediol dicarbamate; a commonly prescribed, centrally acting skeletal muscle relaxant. Neuroleptic malignant syndrome (NMS) is a potentially life-threatening adverse effect of antipsychotic agents. Although diagnostic criteria for NMS have...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Journal of Anaesthesiology Clinical Pharmacology |
| Subjects: | |
| Online Access: | http://www.joacp.org/article.asp?issn=0970-9185;year=2016;volume=32;issue=3;spage=387;epage=388;aulast=Paul |
| _version_ | 1811205375069782016 |
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| author | Gunchan Paul Gautam L Parshotam Rajneesh Garg |
| author_facet | Gunchan Paul Gautam L Parshotam Rajneesh Garg |
| author_sort | Gunchan Paul |
| collection | DOAJ |
| description | Soma (Carisoprodol) is N-isopropyl-2 methyl-2-propyl-1,3-propanediol dicarbamate; a commonly prescribed, centrally acting skeletal muscle relaxant. Neuroleptic malignant syndrome (NMS) is a potentially life-threatening adverse effect of antipsychotic agents. Although diagnostic criteria for NMS have been established, it should be recognized that atypical presentations occur and more flexible diagnostic criteria than currently mandated, may be warranted. We wish to report a postoperative case of bilateral knee replacement who presented with carisoprodol (Soma) withdrawal resembling NMS that was a diagnostic dilemma. Subsequently, it was successfully treated with oral baclofen in absence of sodium dantrolene. |
| first_indexed | 2024-04-12T03:29:51Z |
| format | Article |
| id | doaj.art-c32c3c595982438a90573f03388afcf7 |
| institution | Directory Open Access Journal |
| issn | 0970-9185 |
| language | English |
| last_indexed | 2024-04-12T03:29:51Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Anaesthesiology Clinical Pharmacology |
| spelling | doaj.art-c32c3c595982438a90573f03388afcf72022-12-22T03:49:34ZengWolters Kluwer Medknow PublicationsJournal of Anaesthesiology Clinical Pharmacology0970-91852016-01-0132338738810.4103/0970-9185.173346Carisoprodol withdrawal syndrome resembling neuroleptic malignant syndrome: Diagnostic dilemmaGunchan PaulGautam L ParshotamRajneesh GargSoma (Carisoprodol) is N-isopropyl-2 methyl-2-propyl-1,3-propanediol dicarbamate; a commonly prescribed, centrally acting skeletal muscle relaxant. Neuroleptic malignant syndrome (NMS) is a potentially life-threatening adverse effect of antipsychotic agents. Although diagnostic criteria for NMS have been established, it should be recognized that atypical presentations occur and more flexible diagnostic criteria than currently mandated, may be warranted. We wish to report a postoperative case of bilateral knee replacement who presented with carisoprodol (Soma) withdrawal resembling NMS that was a diagnostic dilemma. Subsequently, it was successfully treated with oral baclofen in absence of sodium dantrolene.http://www.joacp.org/article.asp?issn=0970-9185;year=2016;volume=32;issue=3;spage=387;epage=388;aulast=PaulCarisoprodolcarisoprodol abusecarisoprodol withdrawalneuroleptic malignant syndromesoma |
| spellingShingle | Gunchan Paul Gautam L Parshotam Rajneesh Garg Carisoprodol withdrawal syndrome resembling neuroleptic malignant syndrome: Diagnostic dilemma Journal of Anaesthesiology Clinical Pharmacology Carisoprodol carisoprodol abuse carisoprodol withdrawal neuroleptic malignant syndrome soma |
| title | Carisoprodol withdrawal syndrome resembling neuroleptic malignant syndrome: Diagnostic dilemma |
| title_full | Carisoprodol withdrawal syndrome resembling neuroleptic malignant syndrome: Diagnostic dilemma |
| title_fullStr | Carisoprodol withdrawal syndrome resembling neuroleptic malignant syndrome: Diagnostic dilemma |
| title_full_unstemmed | Carisoprodol withdrawal syndrome resembling neuroleptic malignant syndrome: Diagnostic dilemma |
| title_short | Carisoprodol withdrawal syndrome resembling neuroleptic malignant syndrome: Diagnostic dilemma |
| title_sort | carisoprodol withdrawal syndrome resembling neuroleptic malignant syndrome diagnostic dilemma |
| topic | Carisoprodol carisoprodol abuse carisoprodol withdrawal neuroleptic malignant syndrome soma |
| url | http://www.joacp.org/article.asp?issn=0970-9185;year=2016;volume=32;issue=3;spage=387;epage=388;aulast=Paul |
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