Evaluation of eight live attenuated vaccine candidates for protection against challenge with virulent Mycobacterium avium subspecies paratuberculosis in mice

Evaluation of eight live attenuated vaccine candidates for protection against challenge with virulent Mycobacterium avium subspecies paratuberculosis in mice

Johne’s disease is caused by Mycobacterium avium subsp. paratuberculosis (MAP), which results in serious economic losses worldwide in farmed livestock such as cattle, sheep and goats. To control this disease, an effective vaccine with minimal adverse effects is needed. In order to identify a live...

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Bibliographic Details
Main Authors: John P Bannantine, Jamie L Everman, Sasha eRose, Lmar eBabrak, Robab eKatani, Raul G. Barletta, Adel M Talaat, Yrjo T Grohn, Yung-Fu eChang, Vivek eKapur, Luiz E Bermudez
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Genomics
Mycobacterium
Vaccines, Attenuated
mouse model
Johne's disease
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00088/full

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