Assessment of Aggregated and Exosome-Associated α-Synuclein in Brain Tissue and Cerebrospinal Fluid Using Specific Immunoassays

Assessment of Aggregated and Exosome-Associated α-Synuclein in Brain Tissue and Cerebrospinal Fluid Using Specific Immunoassays

Even though it is currently well-established that α-synuclein aggregation is closely associated with the pathological events in Parkinson’s disease (PD) and several other neurodegenerative disorders, collectively called synucleinopathies, the mechanistic link between α-synuclein aggregates and the o...

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Bibliographic Details
Main Authors: Dimitrios Anagnostou, Garifalia Sfakianaki, Katerina Melachroinou, Miltiadis Soutos, Vassilios Constantinides, Nishant Vaikath, Ioanna Tsantzali, George P. Paraskevas, Omar El Agnaf, Kostas Vekrellis, Evangelia Emmanouilidou
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Diagnostics
Subjects:
α-synuclein
exosomes
CSF
Parkinson’s Disease
fibrils
ELISA
Online Access:https://www.mdpi.com/2075-4418/13/13/2192

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